Schwannoma and its unusual variants-A histopathological study

Patil, Sunita B; Kr, Chatura

doi:10.5958/2394-6792.2016.00135.6

Cited by 4 publications

(5 citation statements)

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“…In the current case series, all the cases showed features of conventional schwannoma consisting of two cellular patterns: Antoni type A and Antoni type B. [ 2 16 17 ]…”

Section: Discussionmentioning

confidence: 91%

“…Degenerative features are represented by areas of hemorrhage, hemosiderin deposits, inflammation, fibrosis, hyalinization, and nuclear atypia. [ 2 7 16 17 ] It is believed that long history of the lesion could be the cause of the transformation to an “ancient” variant. [ 18 ] Out of current case series, one case (Case 1) showed features of ancient schwannoma.…”

Section: Discussionmentioning

confidence: 99%

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Pathological diversity in schwannomas of the orofacial region

et al. 2021

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Schwannoma is a slow-growing, encapsulated benign tumor of the neuroectodermal origin arising from the perineural Schwann cells. This study aims to elucidate the clinicoradiographical and histopathological features of orofacial schwannomas through a case series of seven cases. The patients' aged ranged from 13 to 45 years, with a male predilection in the ratio of 5:2. One intraosseous case presented as a radiolucent lesion. All the cases exhibited Antoni A and Antoni B type of microscopic patterns in varying amounts. One case of ancient schwannoma showed degenerative features. The tumor cells showed diffuse positive immunohistochemical reaction for S-100 protein. Our study suggests that intraosseous schwannoma should be considered in the differential diagnosis of the intraosseous jaw lesions. Histopathologically, it is important to recognize the findings of ancient schwannoma and to avoid misdiagnosing it as a malignant lesion.

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“…In the current case series, all the cases showed features of conventional schwannoma consisting of two cellular patterns: Antoni type A and Antoni type B. [ 2 16 17 ]…”

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Pathological diversity in schwannomas of the orofacial region

et al. 2021

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“…Blood vessels may be present with a hyalinized layer. Immunohistochemically, schwannomas show intense and relatively uniform staining for S-100 protein, which is a marker for Schwann cells [ 4 , 6 , 9 , 11 , 12 , 13 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…Histological schwannoma variants include ancient schwannoma, plexiform schwannoma, cellular schwannoma, epithelioid schwannoma, melanotic (pigmented) schwannoma, schwannoma with pseudoglandular elements, cystic schwannoma, and psammomatous schwannoma. Classical schwannomas are more common and commonly found in the following locations: the head and neck region, followed by the extremities, seen over a wide age range [ 7 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Sciatic Nerve as a Cause of Extra-articular Knee Pain: Case Report and Literature Review

Nkosi,

Chauke

2023

jocr

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Introduction: Schwannomas are rare benign tumors of the nerve sheath that originate from the Schwann cells of the peripheral nerve and have a broad anatomic distribution that includes superficial tissues, deep tissues, including the central nervous system, and the gastrointestinal system. Case Report: A 60-year-old male presented with left knee pain for 5 years. This pain was associated with paresthesia, night pain unresponsive to analgesia, on the left foot intermittent pins and needles sensation. Schwannoma lesion was excised, histology confirmed the diagnosis, and the patient’s symptoms improved. Conclusion: Schwannoma around the knee is a rare or atypical cause of the non-arthritic pain and should be considered in the differential diagnosis of non-arthritic and extra-articular causes of knee pain with neurological deficit of the foot in an adult population. Keywords: Schwannoma, sciatic nerve, knee pain, benign tumor.

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“…Histologically, typical schwannomas are composed of intermixed Antoni A components (cellular and arranged in short bundles or interlacing fascicles) and Antoni B areas (less cellular and organized with more myxoid components). 1 Schwannomas are often large at diagnosis and are frequently locally advanced for malignant tumors. Schwannomas are generally located in the head and neck, mediastinum, and extremities and are extremely rare in the pelvis.…”

Section: Introductionmentioning

confidence: 99%