Polymorphous low-grade adenocarcinoma (PLGA), is a rare, salivary gland intraoral tumor with complexities in diagnosis and this review highlights the difficulties.

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Adamantinoma is an uncommon tumour of low grade malignancy in terms of biologic aggressiveness; metastasis occurring many years after amputation. A young male underwent an above knee amputation of left leg for adamantinoma of tibia. He returned with pain and swelling in his right thigh five years later. Investigations revealed an adamantinoma in the diaphysis of the right femur. The unusual presentation of this adamantinoma at an uncommon site threw up interesting insights into the nature of this lesion. In particular, the metachronous origin of the adamantinoma in the femur is discussed in this report.

Endometrial stromal sarcomas (ESSs) are morphologically heterogenous and diagnosed by light microscopy in most instances. The distinction between smooth muscle neoplasms, such as cellular leiomyoma and low-grade ESS can be problematic. The diagnoses of ESS on the basis of systematic assessment of gross and histological parameters are highlighted.Hysterectomy from four patients for a clinical diagnosis of leiomyoma was studied. Grossly, three had polypoidal lesion and in one myometrial widening with obvious permeation was noted. Microscopy showed features of ESS in three cases. Other case was diagnosed as cellular leiomyoma thought to be endometrial polyp. Reticulin stain was employed to highlight the characteristic spiral arterioles in ESS and thick-walled vessels in cellular leiomyoma.