Schwannoma of the Hand and Wrist

Rockwell, Gloria; Thoma, Achilleas; Salama, Samih

doi:10.1097/01.prs.0000046039.28526.1a

Cited by 74 publications

(63 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The rare schwannoma associated with a digital nerve is more commonly found on the palm [6], but lesions distal to the proximal interphalangeal joint have been described [9,17]. As well, rare intraosseous schwannomas that arise from within bone without an obvious associated nerve have been described [3,4].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Presentation of a Digital Schwannoma: Case Report

Dwyer

Creager

Lubahn

2014

Hand (New York, N,Y.)

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

An Unusual Presentation of a Digital Schwannoma: Case Report

Dwyer

Creager

Lubahn

2014

Hand (New York, N,Y.)

View full text Add to dashboard Cite

“…Multiple tumours were detected in two female patients described by these authors; they derived, however, from separate nerves. Rock well et al did not describe any tumours located peripherally to the proximal interphalangeal joint [27]. Peripheral location of schwannomas in fingers is a subject of casuistic reports [15,32].…”

Section: Discussionmentioning

confidence: 99%

“…Location of solitary schwannomas in the hand and fingers is rare [8,27]. Cases of multiple schwan nomas in this region are of great rarity [41].…”

Section: Discussionmentioning

confidence: 99%

Case report Multiple schwannomas of the digital nerves and superficial radial nerve: two unusual cases of segmental schwannomatosis

Gosk

Gutkowska²,

Kuliński³

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The plexiform schwannoma without NF-2 -as described herein -is a rarity. [8][9][10] Major differential diagnoses include neurofibroma, perineurinoma and the malignant nerve sheath tumor. 1,2 The tactics in treatment follow primarily the wait and see-rule.…”

Section: Discussionmentioning

confidence: 99%

Isolated plexiform schwannoma of the hand

Wollina¹,

Langner²,

Gruner³

et al. 2008

J Dermatol Case Rep

View full text Add to dashboard Cite

Background: The plexiform schwannoma, a peripheral nerve sheath tumor, is a very rare entity. But dermatologists should be familiar with since they may be the first who make diagnosis possible by taking a deep biopsy.Main observation: A 24-year-old male presented with multiple asymptomatic subcutaneous nodules of the palmar side of his right hand. Histologic investigations revealed a plexiform schwannoma with numerous Antoni-A areas. There was no evidence of neurofibromatosis type 1 or 2.Conclusions: Plexiform schwannoma of the hand is a rare nerve sheath tumor. In individual (symptomatic) cases hand surgery is an option that needs a critical indication. In every case histologic investigations are mandatory to confirm the diagnosis and not to overlook the malignant variant of this disease. Imaging diagnostics like 3-dimensional ultrasound and MRI do not allow a sufficient discrimination of schwannomas form other nerve sheath tumors. 4 The only way to confirm the diagnosis is by histopathology. Isolated plexiform schwannoma of the handWe present an unusual case of a large unilateral plexiform schwannoma of the hand in a young male patient. Case ReportA 24-year-old male patient experienced asymptomatic subcutaneous nodules of his right hand since 2000. There was a slow progress in size and number.On examination we found soft, yellowish subcutaneous nodules of variable size of the volar site of the fingers and the palm of his right hand ( Fig. 1A and B).Histology of two biopsies showed spindle-shaped cell proliferations in the dermis and upper subcutaneous tissue with a capsule formation. Cells were characterized by neurogenic differentiation like Antoni-A-areas (Fig. 2).Clinical examination and consiliae did not reveal any sign of neurofibromatosis type 1 or type 2.After confirmation of the diagnosis of a plexiform schwannoma of the right hand the patient was referred to the hand surgeon. He advised not to intervene by surgery because of the risk of paresis and the completely asypto- DOI: 10.3315/jdcr.2008DOI: 10.3315/jdcr. .1011 28 matic course without functional handicap in this patient.Follow-up has been recommended by us. DiscussionSchwannomas are benign tumors of the nerve sheath occuring either peripheral, visceral, intraspinal or intracranial. Peripheral schwannomas represent as asymptomatic and painless papules or nodules. Their colour can be yellowish to light brown. Cysts and haemorrhages may occur. Schwannomas of the hands are rare. Patient's mean age at diagnosis is 38.4 years. 5 Histology is characterized by a biphasic pattern with tightly packed spindle-shaped cells (Antoni A area) and with loose, less cellular patterns with myxoid areas with thickened "hyalinized" vessel walls (Antoni B) and lipidcontaining cells. 3 Mitoses are usually absent but pleomorphism of nuclei is common. Immunohistochemistry is helpful in differential diagnosis ( Table 1). The tumor cells express S-100 protein. 1,2 Complicating in differential diagnosis is the observation of collision tumors like schwannoma and peri...

show abstract

Schwannoma of the Hand and Wrist

Cited by 74 publications

References 12 publications

An Unusual Presentation of a Digital Schwannoma: Case Report

An Unusual Presentation of a Digital Schwannoma: Case Report

Case report Multiple schwannomas of the digital nerves and superficial radial nerve: two unusual cases of segmental schwannomatosis

Isolated plexiform schwannoma of the hand

Contact Info

Product

Resources

About