Schwefelkohlenstoffvergiftung und das sulfocarbotoxische vascul�re Sp�tsyndrom

Toxic Solvents: A Review

“…The vascular disturbance appears to be an arterioor atherosclerotic change in the small arteries of the brain and medulla, giving rise to a diffuse encephalopathic reaction, showing itself as hypertension or nephrosclerosis. According to von Rechenberg (1957), this syndrome, first described by Vigliani and Cazzullo in 1950, as " encephalopathia diffusa sulphocarbonica " appears only after 10 to 15 years' exposure, and once subacute symptoms have appeared is rapidly progressive. The disease has a slow, insidious onset and its development is punctuated by episodes of transient hemiplegia or spastic paresis.…”

“…The nephrosclerotic form is accompanied by hypertonia, albuminuria, microhaematuriawith casts, and optic disc changes (von Rechenberg, 1957). The actual distribution of the carbon disulphide, which is not eliminated in the expired air or urine, in the various organs and tissues is not at present completely understood nor is it certain whether quantitative determination of very small amounts of CS2 in the blood will have diagnostic significance in cases of possible chronic poisoning.…”