Sci—Sat AM: Brachy — 10: Adaptation of the CVT algorithm for catheter optimization in high dose rate brachytherapy

Poulin, Éric C.; Fekete, C. Collins; Morrier, Janelle; Varfalvy, Nicolas; Pouliot, Jean; Beaulieu, Luc

doi:10.1118/1.4740217

Cited by 2 publications

(1 citation statement)

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“…Both methods require a manual pre-selection of potential catheters positions. Currently, there are three methods that address catheter configuration optimization for prostate HDR brachytherapy: a centroidal voronoi tessellation (CVT) algorithm for fast needle selection (Poulin et al 2012), hybrid inverse planning and optimization (HIPO) (Karabis et al 2009) and the reformulation of the dose-based optim ization into a mixed-integer-linear-programming (MILP) problem (Gorissen et al 2013). The latter provides solutions that represent the global optimum.…”

Section: Introductionmentioning

confidence: 99%

Real-time inverse high-dose-rate brachytherapy planning with catheter optimization by compressed sensing-inspired optimization strategies

Guthier¹,

Aschenbrenner²,

Müller³

et al. 2016

Phys. Med. Biol.

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This paper demonstrates that optimization strategies derived from the field of compressed sensing (CS) improve computational performance in inverse treatment planning (ITP) for high-dose-rate (HDR) brachytherapy. Following an approach applied to low-dose-rate brachytherapy, we developed a reformulation of the ITP problem with the same mathematical structure as standard CS problems. Two greedy methods, derived from hard thresholding and subspace pursuit are presented and their performance is compared to state-of-the-art ITP solvers. Applied to clinical prostate brachytherapy plans speed-up by a factor of 56-350 compared to state-of-the-art methods. Based on a Wilcoxon signed rank-test the novel method statistically significantly decreases the final objective function value (p < 0.01). The optimization times were below one second and thus planing can be considered as real-time capable. The novel CS inspired strategy enables real-time ITP for HDR brachytherapy including catheter optimization. The generated plans are either clinically equivalent or show a better performance with respect to dosimetric measures.

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Section: Introductionmentioning

confidence: 99%

Real-time inverse high-dose-rate brachytherapy planning with catheter optimization by compressed sensing-inspired optimization strategies

Guthier¹,

Aschenbrenner²,

Müller³

et al. 2016

Phys. Med. Biol.

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A fast inverse treatment planning strategy facilitating optimized catheter selection in image‐guided high‐dose‐rate interstitial gynecologic brachytherapy

et al. 2017

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The proposed heuristic for needle selection provides fast catheter selection with optimization times suited for intraoperative treatment planning. Compared to manual optimization, the proposed methodology results in fewer catheters without a clinically significant loss in plan quality. The proposed approach can be used as a decision support tool that guides the user to find the ideal number and configuration of catheters.

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Sci—Sat AM: Brachy — 10: Adaptation of the CVT algorithm for catheter optimization in high dose rate brachytherapy

Cited by 2 publications

References 0 publications

Real-time inverse high-dose-rate brachytherapy planning with catheter optimization by compressed sensing-inspired optimization strategies

Real-time inverse high-dose-rate brachytherapy planning with catheter optimization by compressed sensing-inspired optimization strategies

A fast inverse treatment planning strategy facilitating optimized catheter selection in image‐guided high‐dose‐rate interstitial gynecologic brachytherapy

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