Sciatic nerve hypertrophy with klippel trenaunay syndrome: a case report

Abstract

A 73-year-old female patient who had severe neuropathic pain due to sciatic nerve hypertrophy with the Klippel-Trenaunay Syndrome has been presented. Localized hypertrophic neuropathy is in one region and characterized by concentric proliferation of Schwann cells around the axon. It is very rare in the absence of generalized hypertrophic neuropathy. Very little is known about the etiology and the course of this neuropathy. Klippel-Trénaunay-Syndrome (KTS) is a rare syndrome characterized by hemangioma, abnormalities of the venous and lymphatic systems, and limb enlargement due to soft tissue and bone hypertrophy.

Port-Wine Stain and Monomelic Weakness Associated With Perineurioma: A Neuromuscular Image

“…10 Previously described peripheral nerve biopsy findings in KTS include localized hypertrophic neuropathy, fibrolipomatous hamartoma, lipoma, and microscopic epineural arteriovenous anastomoses. [11][12][13][14] Our patient did not have the characteristic clinical, radiographic, or biopsy findings to support KTS.…”

Síndrome de Parkes Weber en un neonato: reporte de un caso

“…Gran parte de la morbimortalidad del síndrome de Parkes Weber es debido a la vasta cantidad de complicaciones y de malformaciones de los diferentes órganos y sistemas. Aquellos pacientes con obstrucción del drenaje linfático tienen mayor riesgo de fallecer por celulitis y bacteriemia 10 .…”

Nerve conduction assessment and magnetic resonance imaging for the diagnosis of localized hypertrophic neuropathy of the sciatic nerve and the lumbo-sacral plexus

“…A confined whorl proliferation of Schwann cells and fibrous tissues wrapping a variably myelinated axons of peripheral nerves [4,5]. LHN most frequently involves the brachial plexus and the radial, median, sciatic, peroneal, tibial and trigeminal nerves [4,6]. LHN of the sciatic nerve was reported in a 73-year-old man affected by Klippel-Trenaunay Syndrome, a rare congenital vascular disorder in which a limb may be affected by port wine stains [6]f.…”

“…LHN most frequently involves the brachial plexus and the radial, median, sciatic, peroneal, tibial and trigeminal nerves [4,6]. LHN of the sciatic nerve was reported in a 73-year-old man affected by Klippel-Trenaunay Syndrome, a rare congenital vascular disorder in which a limb may be affected by port wine stains [6]f. LHN of spinal nerve rootsfrom the conus into the upper leghave also be reported [4].…”