Scintigraphic detection of splenosis: Superiority of tomographic selective spleen scintigraphy

Pitfalls in oncology: a unique case of thoracic splenosis mimicking malignancy in a patient with resected breast cancer

“…demonstrated that 99mTc-RBC scan is more sensitive and specific when compared with 99mTc sulfur colloid one in detecting splenosis, with a difference in terms of sensitivity reaching 32% (13,14). This behavior renders these radionuclide scans the current diagnostic methods of choice.…”

Contribution of the single photon emission computed tomography with 99mTc red blood cells in splenosis

“…Splenosis has been reported mainly in the left segment of the abdomen, but it can also occur in the chest when diaphragm is damaged after a trauma. 1,2,4 The average interval reported between trauma and abdominal or pelvic splenosis is 10 years, with a range of 5 months to 32 years. 10 In order of frequency, the most common sites are the serosal surface of the small bowel, greater omentum, parietal peritoneum, serosal surface of the large intestine and mesentery.…”

“…10 In order of frequency, the most common sites are the serosal surface of the small bowel, greater omentum, parietal peritoneum, serosal surface of the large intestine and mesentery. 2 However, unusual sites of splenic tissue, such as extensive involvement in the liver, pancreas, stomach, kidneys, ureters, bladder, uterus, or fallopian tubes have also been previously described. 4 Splenosis is generally observed in multiple rather than solitary locations, as its primary mechanism of auto transplantation initiated with the splenic rupture is the seeding of damaged splenic pulp into adjacent cavities, similar to endometriosis or malignancy ( Figure 1).…”

“…4 Splenosis is generally observed in multiple rather than solitary locations, as its primary mechanism of auto transplantation initiated with the splenic rupture is the seeding of damaged splenic pulp into adjacent cavities, similar to endometriosis or malignancy ( Figure 1). 2 An alternative probability of intrahepatic splenosis is that the splenic tissue and cells migration to the subcapsular location in the liver through the blood or lymphatic vessels after trauma. 11 In this regards, Kwok et al 12 hypothesized that the migration of erythrocytic progenitor cells through the portal vein following traumatic splenic rupture could promote intrahepatic splenosis development.…”

Splenosis and sepsis: The born-again spleen provides poor protection

“…6,54,55 Even thoracic splenosis, a less common presentation, may exist in up to one-fifth of patients with simultaneous splenic and diaphragmatic injury. 56 When imaging reveals a splenic nodule that may have otherwise gone unnoticed, the clinician faces a diagnostic dilemma, particularly in the case of intrathoracic or intrahepatic masses.…”