Sclerosing polycystic adenosis: A case report with review of the literature

Appasani, Sreelekha; Ramadas, Preethi T; Gangadharan, Jayapriya; Mathews, Anitha

doi:10.4103/ijpm.ijpm_518_17

Cited by 5 publications

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“…No study could diagnose SPA only with FNAC 12 . In several cases, the diagnosis was given as pleomorphic adenomas or other benign lesions 12,14–22 . Nevertheless, FNAC proved to be beneficial because it ruled out the presence of a malignancy in most of the cases.…”

Section: Discussionmentioning

confidence: 99%

“…An important feature found in SPA cases is intraductal epithelial proliferations associated with cellular atypia, that range from mild to invasive carcinoma. [2][3][4]7,9,10,12,14,16,17,21,23,[34][35][36][37][38][39][40] The presence of these cellular alterations combined with molecular alterations leads to some authors' conclusion that SPAs are neoplasms rather than reactive inflammatory lesions and should be referred to as sclerosing polycystic adenoma. 9,10 All patients described in previous reports received different forms of treatment including conservative surgery was the most common form of treatment.…”

Section: Discussionmentioning

confidence: 99%

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Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review

et al. 2023

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In this systematic review, we aimed to evaluate the clinicopathological profile of sclerosing polycystic adenoma (SPA). PubMed, Scopus, EMBASE, Lilacs, Web of Science, and gray literature were searched to access cases of SPA in salivary glands. One hundred and thirty cases of SPA were found across 61 selected articles. SPA affected mainly the parotid gland of adults with a mean age of 44.6 years old, with a slight preference for females. The lesion was usually presented as a painless firm mass with a long period of evolution. Histologically, they are well‐delimitated lesions composed of acinar and ductal elements with a variety of cytomorphologic features surrounded by a densely collagenized stroma. PI3K was the most common gene mutation related to SPA. SPA is a benign condition that mainly affects the parotid gland of female patients and it is usually treated by surgical resection with a good prognosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review

et al. 2023

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Sclerosing polycystic adenoma – A review

Petersson

2022

Annals of Diagnostic Pathology

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Case of labial sclerosing polycystic adenoma with ductal carcinoma in situ (DCIS)

et al. 2021

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Minor salivary gland tumours are enigmatic in their behaviour and presentations. Histopathological diagnosis of these tumours encompasses a large spectrum. Conventionally, small nodular tumours of the upper lip or the labial mucosa are generally adenomas, frequently pleomorphic adenomas. Here, we describe a case of a solitary nodular tumour, occurring in the upper labial mucosa, diagnosed as sclerosing polycystic adenoma (SPA) with intraductal epithelial proliferation of high grade. This is a rare lesion, which has entered into the category of salivary gland tumours recently in the 2017 WHO categorisation. We report a case of paucicystic SPA with intraductal epithelial proliferations in the labial minor salivary gland of a 56-year-old woman, which might be the first report of a case occurring in the upper labial mucosa.

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Sclerosing polycystic adenosis: A case report with review of the literature

Cited by 5 publications

References 0 publications

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review

Sclerosing polycystic adenoma – A review

Case of labial sclerosing polycystic adenoma with ductal carcinoma in situ (DCIS)

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