Sclerotherapy treatment of orbital lymphatic malformations: a large single-centre experience

Abstract

Sclerotherapy is a safe and highly effective treatment for orbital LMs with excellent VA outcomes. It should be considered as the first-line treatment for this condition.

Management of a case of orbital lymphangioma presenting in adulthood with negative-pressure aspiration and bleomycin injection

“…Intralesional sclerotherapy has been tried in children and young adults for lymphangiomas with optimal results 14. The endothelial lining of these lesions is vulnerable to infections and chemical irritants, causing their regression.…”

Sclerotherapy for Orbital Lymphangioma – Case Series and Literature Review

“…It is important to remain in frequent communication with the patient and/or their parents, as well as colleagues, to ensure a consistent message and plan of action. What is clear is that sclerotherapy is now an established management option for these lesions, with good results (and minimal complications) in appropriately chosen patients (8).…”

Orbital Lymphangioma-Case Report and Review of the literature

“…There is no definitive treatment, although there are several sclerotherapy options as a new line of treatment to reduce recurrence rates or in unresectable cases. Some of these agents include OK 432, sodium tetradecylsulfate, sodium morrhuate and bleomycin, the latter being the preferred agent in the last couple of years [11][12][13] . Bleomycin, a glucopeptide produced by Streptomyces Verticilus, which acts by breaking DNA chains with free radicals, affects tumor cells.…”