“…The animals were randomly divided into five groups ( n = 8 in each), as follows: - Sham‐operated group : Normal saline was intraperitoneally (ip) injected (0.3 ml) for 18 days, and laparotomy without ureteral ligation was performed on the fourth day of the experiment.
- UUO group : Normal saline was injected (0.3 ml, ip) for 18 days, and laparotomy and ligation of the left ureter were performed on the fourth day of the experiment.
- Los + UUO group : Losartan was injected (0.3 ml equal to 15 mg/kg, ip; Manucha, Carrizo, Ruete, Molin, & Valles, ; Radović et al, ) daily for 18 days, and laparotomy and ligation of the left ureter were performed on the fourth day of the experiment.
- Cap + UUO group : Captopril was injected (0.3 ml equal to 30 mg/kg; Larivière et al, ; Hosseinian, Ebrahimzadeh Bideskan, et al, ) for 18 days, and laparotomy and ligation of the left ureter were performed on the fourth day of the experiment.
- TQ + UUO group : TQ was injected (0.3 ml equal to 10 mg/kg; Hosseini et al, ) for 18 days, and laparotomy and ligation of the left ureter were performed on the fourth day of the experiment.
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