2023
DOI: 10.1002/prot.26633
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MPA‐Pred: A machine learning approach for predicting the binding affinity of membrane protein–protein complexes

Fathima Ridha,
M. Michael Gromiha

Abstract: Membrane protein–protein interactions are essential for several functions including cell signaling, ion transport, and enzymatic activity. These interactions are mainly dictated by their binding affinities. Although several methods are available for predicting the binding affinity of protein–protein complexes, there exists no specific method for membrane protein–protein complexes. In this work, we collected the experimental binding affinity data for a set of 114 membrane protein–protein complexes and derived s… Show more

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