“…5 The emergence of the National Primate Research Centers, which were established to ensure that scientists would have the specialized resources needed to conduct primate research, owe their origins to the millions of macaques removed from the wild during the 1940s and 1950s. 6 However, by the late 1960s rhesus macaque populations in India had declined by 90%. 7 This staggering population decrease, coupled with the revelation that the United States had violated a 1955 agreement which required that (1) use of Indian rhesus macaques be restricted to medical research and vaccine production, (2) the US Public Health Service certify every project using the Indian-origin macaques, (3) the US establish an Advisory Committee on Rhesus Monkey Requirements, and (4) the monkeys were to be used humanely, and explicitly not used in atomic blast experiments or space research, led to an eventual ban on the exportation of Indian-origin rhesus macaques to the US.…”