US–National Institutes of Health‐funded research for cutaneous wounds in 2012

Abstract

Chronic cutaneous wounds are a major burden on patients, healthcare providers, and the US healthcare system. This study, carried out in part by the Wound Healing Society's Government Regulatory Committee, aimed to evaluate the current state of National Institutes of Health funding of cutaneous wound healing-related research projects. National Institutes of Health Research Portfolio Online Reporting Tools Expenditures & Results system was used to identify wound healing projects funded by the National Institutes of Health in the 2012 fiscal year. Research projects focusing on cutaneous wound prevention/education, mechanisms, complications, treatment, or imaging/monitoring were included in the analysis. Ninety-one projects were identified, totaling a collective funding of $29,798,991 and median funding of $308,941. Thirteen institutes/centers from the National Institutes of Health were responsible for awarding funds; three of which (National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases) accounted for 60.4% of the grant funding. The predominant funding mechanisms included R01 (48.3%), R43 (14.3%), and R21 (9.9%). New applications and pre-existing applications accounted for 39.6 and 55.0% of the awarded grants, respectively. Grants awarded to investigators affiliated with universities accounted for 68.1% of grants and 25.3% were to investigators in the private sector. This analysis of current National Institutes of Health funding may facilitate more transparency of National Institutes of Health-allocated research funds and serve as an impetus to procure additional support for the field of wound healing.

Academic characteristics for successful national institutes of health funding in dermatology

“…In 2012, only 18% of grant applications successfully achieved funding from the NIH, a sharp decline from the 31% success rate 10 years earlier [4]. Given that NIH funding is so valuable and increasingly more difficult to come by, the aim of this study was to determine the academic characteristics of successful NIH funding recipients in the department of dermatology.…”

“…Several studies have used NIH funding as a marker of success [1][2][3][4][5][6][7][8][9][10]. NIH funding strengthens academic departments by allowing the department to invest funding into long-term development, hire extra faculty, and increase research productivity.…”

Influence of Melanine on Morphofunctional Indices of Rat Skin With Chemical Burner and Full-Thickness Wound

“…Загоєння ран являє собою запрограмований процес, що складається з 3 безперервних фаз [8]: запальної реакції -(0-3 днів), клітинної проліферації -(3-12 днів), і ремоделювання -(3-6 міс) [9][10][11]. Порушення однієї із фаз ранового процесу може перервати процес загоєння рани і привести до ускладнень (три-вало незагоювання) [8].…”

Advances in the treatment of chronic wounds: a patent review

“…Chronic wounds also create a significant economic burden with nearly 2% of the health budgets devoted to the care of chronic wounds and hospitalization. In the US alone, chronic wounds affect > 6 million patients annually, costing the health care system an estimated US$ 20 --25 billion [1]. On a global scale, > 380 million people suffer from diabetes, with approximately 15% of them having a diabetic foot ulcer which is responsible for approximately 80% of all lower leg amputations [2].…”

“…Chronic wounds are associated with high rates of mortality. Diabetic foot ulcers are especially lethal, with mortality rates higher than observed in many common cancers [1]. Chronic wounds also create a significant economic burden with nearly 2% of the health budgets devoted to the care of chronic wounds and hospitalization.…”