Screening Accuracy of Level 2 Autism Spectrum Disorder Rating Scales

Norris, Megan; Lecavalier, Luc

doi:10.1177/1362361309348071

Cited by 193 publications

(134 citation statements)

References 40 publications

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“…Assessment of child development was based on short versions of validated screening tools completed by the mothers at child ages 6, 18 and 36 months (31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44). The instruments measure whether the child has reached critical developmental milestones, or show signs of abnormal behavior.…”

Section: Child Developmentmentioning

confidence: 99%

Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuropsychiatric

Bjørk¹,

Veiby²,

Spigset³

et al. 2014

Nor J Epidemiol

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Introduction: Antiepileptic drug (AED) teratogenicity is suspected to be the main cause of impaired development in children of women with epilepsy. However, many factors may confound the reported risks. The purpose of this review is to characterize the epilepsy cohort in the Norwegian Mother and Child Cohort Study (MoBa) and show how it can be used to detangle various risk factors for adverse outcome in children of mothers with epilepsy. Methods: MoBa is a large, long-term prospective, family-based cohort study. The database is linked to the Medical Birth Registry of Norway. The epilepsy cohort consists of mothers and their children representing more than 700 pregnancies. Blood samples were obtained from the mother during pregnancy and from the umbilical cord after delivery, and AED concentrations were measured. Validated screening tools determined the frequency of maternal confounding risk factors and adverse offspring outcomes. Risk estimates were reported as adjusted odds ratios with confidence intervals using the remaining MoBa cohort as a reference (n=107,597). Outcome in offspring of women with epilepsy without AED treatment in pregnancy and of fathers with epilepsy were used to separate the effect of epilepsy from the effect of in utero exposure to AEDs. Results: Socioeconomic and psychiatric risk factors for adverse offspring outcomes were more frequent in mothers with epilepsy. The frequency of adverse offspring outcome was increased at 6, 18 and 36 months for verbal, motor and social development. Children of women with epilepsy without AED treatment and of fathers with epilepsy were generally similar to children of women without epilepsy. Conclusion: Children of mothers with epilepsy are at risk of adverse outcomes. AED exposure emerges as the most important risk factor.

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Section: Child Developmentmentioning

confidence: 99%

Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuropsychiatric

Bjørk¹,

Veiby²,

Spigset³

et al. 2014

Nor J Epidemiol

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“…In a review, Norris & Lecavalier [27] examined five care-giver completed rating scales for screening for ASD. The scales reviewed were: the Social Communication Questionnaire (SCQ) [9], Gilliam Autism Rating Scale/Gilliam Autism Rating ScaleSecond Edition (GARS/GARS-2) [14], Social Responsiveness Scale (SRS) [11], Autism Spectrum Screening Questionnaire (ASSQ) [28], and Asperger Syndrome Diagnostic Scale (ASDS) [29].…”

Section: Discussionmentioning

confidence: 99%

The Observation Scale for Autism (OSA): A New Screening Method to Detect Autism Spectrum Disorder before Age Three Years

Haglund

Dahlgren

Källén

et al. 2016

J. Intellect. Disabl. Diagn. Treat.

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Background: There is an increasing body of evidence that early interventions for children with Autism Spectrum Disorder (ASD) promote a positive development of social interaction. Thus, tools for early detection of ASD are warranted. Aim: Development of, and deciding cut-off-levels for, a new screening tool for ASD, the Observation Scale for Autism (OSA). The OSA was designed to be used at the free health check-up at 30 months, offered to all children in Sweden. Method: The OSA consists of 12 observations and takes less than 10 minutes to use. The performance of the test was investigated by assessing 37 children previously diagnosed ASD, 23 with Down Syndrome (DS) and 26 typically developing children (TD). Results: Children diagnosed with ASD showed statistically significant higher scores in all 12 items compared to TD children, and significantly higher in 10 items compared to the children with DS. Most of the observations in OSA seemed to cover specific symptoms of ASD, but two of the observations were more related to developmental level. The nine most discriminative items for ASD were identified, and among those, a cut-off limit was chosen (≥3 items). Among children with ASD, 34/37 reached the proposed cut off, compared to 0/26 and 4/23 among children in the TD and DS groups, respectively. Conclusion: The results suggest that the OSA discriminates children with ASD from TD children and children with DS. Using the suggested cut off, OSA provides high sensitivity for ASD (92%) with a very low false positive rate.

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“…Level two screeners are typically not used for screening in a primary care setting. Level two screeners for ASD for children aged three and above have been recently reviewed (Norris and Lecavalier 2010), and will not be considered here.…”

Section: Characteristics Of Screening Toolsmentioning

confidence: 99%

Screening Young Children for Autism Spectrum Disorders in Primary Practice

Barton

Dumont-Mathieu

Fein

2011

J Autism Dev Disord

124

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The increasing prevalence of autism spectrum disorders as well as emerging evidence of the efficacy of early intervention has focused attention on the need for early identification of young children suspected of having an ASSD. Several studies have suggested that while parents report concerns early in development, it may be months before children can be evaluated and services provided, and these delays may be even more marked in under-served populations. The American Academy of Pediatrics recently recommended universal screening for autism spectrum disorders at the 18- and 24-month well-child pediatric visit. The authors review several early screening tools currently in use and offer recommendations for integrating autism specific screening into primary care practice.

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Screening Accuracy of Level 2 Autism Spectrum Disorder Rating Scales

Cited by 193 publications

References 40 publications

Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuropsychiatric

Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuropsychiatric

The Observation Scale for Autism (OSA): A New Screening Method to Detect Autism Spectrum Disorder before Age Three Years

Screening Young Children for Autism Spectrum Disorders in Primary Practice

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