Screening Anxiolytic Activities of Methanolic Fruit Extracts of Spondia Pinnata Plant

Noor, Jannatun; Nipa, Jasmin Ara; Jahan, R; Hussain, Saddam; Islam, Safiqul

doi:10.7897/2230-8407.0711121

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…Jannatun et al, 107 reported anxiolytic activity of S. pinnata fruit methanolic crude extract using hole broad test method and elevated plus maze test method in mice. The diazepam was utilised as a standard.…”

Section: Anxiolytic Activitymentioning

confidence: 99%

A Tangy Twist Review on Hog-Plum: Spondias pinnata (L.f.) Kurz

Mondal

Bhar²,

Panigrahi

et al. 2021

JNR

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Spondias pinnata (L.f.) Kurz., belongs to the Anacardiaceae family, generally referred to as Indian Hog plum, a deciduous, glabrous tree with a healthy fruit to eat. Hog plum is a mild deciduous tree plant of high nutritional value, stubby calories and abundant in vegetable proteins, zinc, chitin, starch, vitamins and minerals. Traditional use of various parts of S. pinnata includes diarrhea, dysentery, stomach troubles, hyperacidity, wounds, sprain, rheumatism, gonorrhoea, tuberculosis, aphrodisiac, arrow poison antidote, dyspepsia, dysentery, ring worms, abscess painful joints, refrigerant, tonic, antiseptic, astringent, mental disorders, tuberculosis, vomiting and many more. A number of pharmacological activities were reported from several extracts of S. pinnata and its parts that include hypoglycemic, anti-cancer, ulcer-protective, antidiarrhoeal, anti-microbial, hepatoprotective, thrombolytic, anti-inflammatory, antiarthritic, analgesic, antipyretic, antihypertensive, anthelmintic, diuretic and laxative, anti-tuberculosis, cytotoxic, antioxidant, anti-hyperlipidemic, ischemia reperfusion injury and preconditioning of heart, anxiolytic, reduce side effects of chemotherapy, ameliorating, platelet aggregation inhibitory activity and acute and sub-chronic toxicity. A few phytochemicals were detailed on this plant. The chemical components of S. pinnata include different amino acids, carbohydrates, terpenoids, flavonoids, polysaccharides, steroids and so on. Various solvent extract and their gas chromatography-mass spectrometry analysis have confirmed the structures of a number of important phytoconstituents. Hence this review can be a good reference for researchers who would undertake further investigation about S. pinnata.

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Section: Anxiolytic Activitymentioning

confidence: 99%

A Tangy Twist Review on Hog-Plum: Spondias pinnata (L.f.) Kurz

Mondal

Bhar²,

Panigrahi

et al. 2021

JNR

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Spondias pinnata (L.f.) Kurz.

Devkota

Sai

2023

Himalayan Fruits and Berries

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Anxiolytic and antidepressant potential of methanol leaf extract of Cassia singueana f. (fabaceae)

Alkali

Abubakar

Musa

et al. 2019

GSC Biol. and Pharm. Sci.

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Depression belongs to a class of mental health disorders termed affective disorders. Affective disorders are disorders related to mood rather than cognitive or thought disturbances. Anxiety is defined as an exaggerated feeling of apprehension, uncertainty and fear. It is an unpleasant state of tension with an anticipation of imminent danger. This research was aimed at evaluating the anxiolytic and antidepressant property of methanol leaf extract of Cassia singueana using Hole Board Test, Open field test, Force swim test and Tail suspension test. The anxiolytic activity was evaluated with adult mice using the hole-board test, elevated plus maze, and open field test. Thirty albino mice were used for each model at the dose of 100, 200 and 400 mg/kg extract for second, third and fourth group respectively. First group is negative control that received distilled water and fifth received 1mg/kg diazepam. The antidepressant potential was evaluated using force swim test and tail suspension models. Thirty rats were used in each of the model, in which they were divided into five groups of six rats each. 2 nd , 3 rd and 4 th group received 100, 200, and 400 mg/kg extract respectively. The first group received distilled water and 5th group received Imipramine 10mg in both the two models. In the hole board test, the extract significantly (p<0.05) increased the number of head dips at 100mg/kg. At a dose of 200 mg/kg the extract prolonged the time spent in the open arm in the elevated plus maze. At the doses of 100 and 200 mg/kg, the extract increased the exploratory behavior in the open field test. In the forced swim and tail suspension test, Cassia singueana methanol leaf extract significantly reduced the duration of immobility of wistar rats. From this results obtained, it can be concluded Cassia singueana methanol leaf extract contained phytochemicals with possible anxiolytic and antidepressant activity.

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Screening Anxiolytic Activities of Methanolic Fruit Extracts of Spondia Pinnata Plant

Cited by 3 publications

References 11 publications

A Tangy Twist Review on Hog-Plum: <i>Spondias pinnata</i> (L.f.) Kurz

A Tangy Twist Review on Hog-Plum: <i>Spondias pinnata</i> (L.f.) Kurz

Spondias pinnata (L.f.) Kurz.

Anxiolytic and antidepressant potential of methanol leaf extract of Cassia singueana f. (fabaceae)

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