Screening of Enrofloxacin and Ciprofloxacin Residues in Chicken Meat by High-Performance Liquid Chromatography

Verma, Megha; Ahmad, A. H.; Pant, Disha; Rawat, Parul; Sharma, S. K.; Arya, Nidhi

doi:10.9734/jpri/2020/v32i2130753

Cited by 18 publications

(10 citation statements)

References 14 publications

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“…In this study, tetracycline and doxycycline were not detected in all samples, which is consistent with the findings of another study conducted in Ethiopia that reported none of the samples had a detectable tetracycline and doxycycline residues. 18 However, the current findings are lower than those reported in India 37 which found about 18.89% and Tanzania 38 reported 35% of samples positive for oxytetracycline.…”

Section: Discussioncontrasting

confidence: 64%

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Determination of Tetracycline Residues in Kidney and Muscle of Beef Cattle Slaughtered in Dire Dawa and Harar Municipal Abattoirs, Eastern Ethiopia

Mohammed¹,

Mengistu

Abdurehman

et al. 2022

Environ�Health�Insights

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Background: Antibiotics are among the most widely used drugs in farm animals for therapeutic and prophylactic purposes. However, the antibiotic residues in meat are a serious public health concern due to their harmful effects on consumer health. Besides this problem, there is limited information on the level of the antibiotic residues, including tetracycline residues. Therefore, this study was aimed to determine the tetracycline residues in the kidney and muscle samples of beef cattle in Harar town and Dire Dawa city. Methods: A study was conducted on 500 randomly selected carcass (250 kidney and 250 muscle samples) slaughtered at Dire Dawa and Harar municipal slaughterhouses between December 2018 and December 2019. The samples were collected aseptically and screened for tetracycline residues by thin layer chromatography. Then, presumptive positive samples were analyzed using high-performance liquid chromatography to get a quantitative outcome. Descriptive statistics were used to determine the frequency, mean, or standard deviation to determine the summary values and distribution of the outcomes. Finally, the data was analyzed using SPSS version 21 software. Results: Out of 500 samples, oxytetracycline residues were detected in 84% of the samples. However, tetracycline and doxycycline were not detected in all samples. Among the kidney and muscle samples collected from Dire Dawa and Harar abattoirs, 109 (87.2%) and 101 (80.8%) were positive for oxytetracycline, respectively. Oxytetracycline residue levels in Dire Dawa ranged from 57 to 607 µg/kg for the kidney and 10.14 to 435 µg/kg for muscle samples. Among the samples collected from Harar, the concentration of oxytetracycline residues ranged from 16 to 433 µg/kg and 6 to 435 µg/kg for kidney and muscle samples, respectively, at Harar slaughterhouses. About 22.0% of muscle samples collected from Dire Dawa and 17.8% from Harar town had oxytetracycline residues above maximum residue limits. Conclusions: In general, the study revealed that oxytetracycline residues were prevalent among tetracycline residues analyzed from kidney and muscle samples in the study areas. Thus, there is a risk of consumer exposure to these antibiotic residues that may have human health effects. Therefore, awareness creation and strict regulation is needed by the regulatory authorities for the use of antimicrobial drugs in the livestock industry.

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Section: Discussioncontrasting

confidence: 64%

“…7 The study conducted in India reported a higher prevalence, which accounted for 33%. 37 The variation may be related to the types of samples analyzed to determine antibiotics, the latter being used in seafood. However, the study conducted in Tanzania reported that none of the samples contaminated with oxytetracycline exceeded MPL.…”

Section: Discussionmentioning

confidence: 99%

Determination of Tetracycline Residues in Kidney and Muscle of Beef Cattle Slaughtered in Dire Dawa and Harar Municipal Abattoirs, Eastern Ethiopia

Mohammed¹,

Mengistu

Abdurehman

et al. 2022

Environ�Health�Insights

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“…(2018 ) discovered ciprofloxacin residues with a mean of 24.8 ± 23.5. Verma et al . (2020 ) looked for ciprofloxacin residues in the muscle, liver, kidney, and fat of broiler chickens but found none in the gizzard, muscle, or heart.…”

Section: Discussionmentioning

confidence: 99%

Assessment of antibiotic residues in chicken meat

Kamouh,

Abdallah,

Kirrella

et al. 2024

Open Vet J

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Background: Nowadays Veterinarians and poultry producers use antibiotics to increase growth rates, bird health, and feed efficiency, egg production, for preventative and therapeutic purposes, and to lessen the prevalence of poultry diseases. Most poultry producers have used a variety of antibiotics, either with or without veterinarian instruction. Although antibiotics are beneficial for the majority of their uses, their unauthorized use has resulted in residues accumulated in poultry products intended for human consumption which represent a serious risk to the general public that could be toxicological, microbiological or immunological. Aim: This study aimed at estimation of the residues of three major antimicrobial used in the intensive chicken rearing systems in Egypt, namely Oxytetracycline, Gentamicin, Ciprofloxacin. Moreover, the effect of cooking on such residues was investigated. Methods: A total of 100 chicken meat samples (breast, thigh, gizzard, liver, 25 each) were examined for detection of the aforementioned antimicrobials using the microbial inhibition assay and HPLC. Besides, samples containing the highest antimicrobial residues were examined for the effect of boiling for 30 min on such residues. Results: The obtained results revealed that 23%, 21%, and 17% of the examined samples were positive for oxytetracycline, gentamicin, and ciprofloxacin residues, respectively. As for cooking (boiling) for 30 minutes showed reduction of the antibiotic residue by 88.2%, 95.2%, and 31.3%, respectively. Conclusion: Antimicrobial residues were detected in the chicken meat parts retailed in Egypt. Cooking can reduce the antimicrobial residues at least in part.

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“…These statistics underscore the substantial reliance on antibiotics within the Indian food-animal sector, posing a significant risk of promoting the emergence and spread of resistance among pathogens ( 12 ). These resistance pathogens have the potential to traverse from animals to humans and the environment through a variety of routes, including direct contact, the presence of antimicrobial residues in food products ( 13 , 14 ), and contamination originating from agricultural waste ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Accessing the behavior and awareness of veterinary professionals towards antimicrobials use and antimicrobial resistance in Indian district

Dhayal,

Rehman,

Krishnan

et al. 2024

Front. Vet. Sci.

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IntroductionAntimicrobial resistance (AMR) poses a significant public health threat, and understanding the awareness and practices of healthcare professionals is crucial for its mitigation. Since the animal sector plays a key role in India’s economy, we decided to explore the understanding of Antimicrobial Use (AMU) and AMR among veterinary professionals.MethodsThe study aimed to evaluate the awareness and behavior of veterinarians and para-veterinarians working in the Jhunjhunu district, Rajasthan, India, concerning AMU and AMR. Questionnaire surveys were administered to them with closed-ended questions. The data was collected and subjected to statistical analysis to derive meaningful insights. The key findings highlight notable differences in certain behavioral aspects of antibiotic prescription among the two groups.Results and DiscussionIt appears that 53.8% of veterinarians as compared to 25.8% para-veterinarians do not surely inform farmers about the importance of adhering to antibiotic withdrawal periods, thereby failing to raise awareness about proper antibiotic use. Moreover, para-veterinarians (46.6%) tend to engage less in evidence-based antibiotic prescription than veterinarians (81%). Furthermore, both groups exhibit a lower frequency of advice on Antimicrobial Susceptibility Testing (ABST), essential for informed prescribing decisions. Most significantly, both groups show a tendency to prefer critically important antibiotics for prescription, raising concerns about the escalating threat of AMR. This study thus emphasizes the areas that need targeted interventions to enhance responsible antimicrobial usage and curb the growth of AMR in the region.

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Screening of Enrofloxacin and Ciprofloxacin Residues in Chicken Meat by High-Performance Liquid Chromatography

Cited by 18 publications

References 14 publications

Determination of Tetracycline Residues in Kidney and Muscle of Beef Cattle Slaughtered in Dire Dawa and Harar Municipal Abattoirs, Eastern Ethiopia

Determination of Tetracycline Residues in Kidney and Muscle of Beef Cattle Slaughtered in Dire Dawa and Harar Municipal Abattoirs, Eastern Ethiopia

Assessment of antibiotic residues in chicken meat

Accessing the behavior and awareness of veterinary professionals towards antimicrobials use and antimicrobial resistance in Indian district

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