Scrotal Hypothermia: New theraphy for poor semen

Zorgniotti, Adrian W.; Sealfon, Andrew I.

doi:10.1016/s0090-4295(84)80006-0

Cited by 22 publications

(14 citation statements)

References 3 publications

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“…Because of its progressive characteristics, varicocele is one of the leading causes of secondary infertility, and several different methods have been defined in the treatment of this common pathology [8,14,16,19,26]. The aim of treatment in varicocele regardless of the method choice is to ligate the internal and external spermatic veins with preserving the vas deferens and its vessels, spermatic artery with its branches and the testicular lymphatics.…”

Section: Discussionmentioning

confidence: 99%

“…Several alternative therapies are developed in the treatment of varicocelectomy due to the progressive impairment in testis functions and its role in the etiology of secondary infertility [10,25]. Hypothermia, percutaneous embolization, laparoscopic and open surgical techniques are widely applied for this reason [8,14,16,19,26]. Open surgery is the most frequently applied and effective technique.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Two Different Microsurgical Methods in the Treatment of Varicocele

Orhan

Onur

Semerciöz

et al. 2005

Archives of Andrology

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& We reviewed records from patients who underwent two different microsurgical varicocelectomy methods: 147 (high inguinal (MHIV) and 65 sub-inguinal (MSIV) microsurgery) to compare the therapeutic activity and complications. Patients who had 2 different microsurgical varicocelectomies were compared according to preoperative connected vein, number of designated arteries, postoperative semen and improvement degree in hormone parameters, increased ratio related with pregnancy and complications. The ratio of improvement of postoperative semen parameters in patients where MHIV and MSIV were performed was, 42% and 38% (p > 0.05). Pregnancy was achieved in MHIV at a ratio of 41% (34=82) and 33% (22=65) in MSIV (p > 0.05). There was no significant difference according to mean operation periods, the vein connected between the groups. The number of testicular arteries were significantly higher than the ones in MHIV (p < 0.01). However, as a postoperative complication, hydrocele was not seen in any of the patients, while relapses occurred in 1 MHIV and 2 MSIV patients. MHIV and MSIV techniques are effective methods to treat varicocele. However, the excess number of connected veins due to the anatomic feature of MSIV increases the possibility of relapses and the technical difficulty during surgical intervention.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of Two Different Microsurgical Methods in the Treatment of Varicocele

Orhan

Onur

Semerciöz

et al. 2005

Archives of Andrology

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“…The link between testicular hyperthermia and transient decreases in semen quality has been demonstrated in men with general hyperthermia such as fever and in scrotal hyperthermia induced by scrotal insulation, frequent hot baths, and the wearing of jockey shorts [46,91,113]. Contradictory claims concerning sauna baths have been reported [105].…”

Section: Hyperthermiamentioning

confidence: 99%

Preventable causes of male infertility

Thompson

1993

World J Urol

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The initial evaluation of the infertile man includes a diligent search for testicular factors, gonadotoxins, and coital factors so as to identify existing causes of impaired fertility and to prevent further dimunition in fertility. There are also prophylactic measures in the treatment of all men that can prevent future infertility, such as prompt correction of cryptorchidism, testicular torsion, genital infection, and adolescent varicocele and proper precautions to limit occupational, medical, and recreational gonadotoxins.

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“…For example, the testicles of males descend in the fetal stage. This is to obtain an internal environment of hypothermia for sperm cell division [27,28]. It is speculated that tumor cell division may similarly or more strictly require hypothermia.…”

Section: Discussionmentioning

confidence: 99%

Internal environment for growth of cancer cells in mice: hypothermia, anemia and lymphocytopenia

Watanabe¹,

Matsumoto

Tomiyama³

et al. 2011

Health

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The internal environment in tumor-bearing mice was investigated in detail. When EL-4 lymphoma cells (5 × 106 cells/mouse) were intraperitoneally inoculated into C57BL/6 mice, approximately 70% of the mice died by day 24. In this regard, the internal environment was compared between control mice, surviving mice and tumor-bearing mice which died. The most prominent sign was hypothermia (<34?C from day 16) seen in tumor-bearing mice which died. Control mice and surviving mice did not show such hypothermia (around 38?C). Other changes, including anemia and lymphocytopenia, were also seen in tumor-bearing mice which died, but not in control mice and surviving mice. Immunological study revealed that NKT cells, which have been previously identified to be the major effector lymphocytes against EL-4 cells, almost disappeared, especially in the liver of tumor-bearing mice which died. These results suggest that a specific internal environment might be required for continuous tumor growth in vivo. Such internal environmental factors include hypothermia, ane- mia and severe immunosuppression

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Scrotal Hypothermia: New theraphy for poor semen

Cited by 22 publications

References 3 publications

Comparison of Two Different Microsurgical Methods in the Treatment of Varicocele

Comparison of Two Different Microsurgical Methods in the Treatment of Varicocele

Preventable causes of male infertility

Internal environment for growth of cancer cells in mice: hypothermia, anemia and lymphocytopenia

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