Dynamic complex matrix inversion (DCMI) problems frequently arise in the territories of mathematics and engineering, and various recurrent neural network (RNN) models have been reported to effectively find the solutions of the DCMI problems. However, most of the reported works concentrated on solving DCMI problems in ideal no noise environment, and the inevitable noises in reality are not considered. To enhance the robustness of the existing models, an anti-noise parameter-variable zeroing neural network (ANPVZNN) is proposed by introducing a novel activation function (NAF). Both of mathematical analysis and numerical simulation results demonstrate that the proposed ANPVZNN model possesses fixed-time convergence and robustness for solving DCMI problems. Besides, a successful ANPVZNN-based manipulator trajectory tracking example further verifies its robustness and effectiveness in practical applications.