Seasonal Exacerbation of Asthma Is Frequently Associated with Recurrent Episodes of Acute Urticaria

Vadasz, Zahava; Kessel, Aharon; Hershko, Alon Y.; Maurer, Marcus; Toubi, Elias

doi:10.1159/000446183

Cited by 13 publications

(16 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All the 8 patients with asthma in our study had positive SPT and all of them had AR meaning that they had allergic asthma, which is in line with other studies showing that seasonal exacerbation of allergic asthma can trigger recurrent episodes of acute urticaria [ 13 ], but joint autoimmune mechanism is the most likely cause of asthma in CSU [ 14 ]. Almost all the patients with atopic dermatitis (AD) had negative SPT at the same time, which is compatible with non-IgE mediated pathophysiology of AD and again autoimmune mechanism can be the cause of this co-morbidity [ 14 ].…”

Section: Discussionsupporting

confidence: 89%

“…trigger recurrent episodes of acute urticaria [13], but joint autoimmune mechanism is the most likely cause of asthma in CSU [14]. Almost all the patients with atopic dermatitis (AD) had negative SPT at the same time, which is compatible with non-IgE mediated pathophysiology of AD and again autoimmune mechanism can be the cause of this co-morbidity [14].…”

Section: Medicine Consumptionmentioning

confidence: 99%

See 1 more Smart Citation

Investigating the association of atopy and aeroallergen sensitization and chronic spontaneous urticaria

Esmaeilzadeh¹,

Eskandarisani²,

Nabavizadeh³

et al. 2022

pdia

View full text Add to dashboard Cite

Introduction: Chronic spontaneous urticaria (CSU) is a common skin allergic reaction with an unknown mechanism. There is inadequate evidence to support the role of aeroallergen sensitization in CSU. Aim: The present study was conducted to investigate the association between the aeroallergen sensitivity and CSU. Material and methods: In this cross-sectional study, 91 patients with CSU were recruited. Information on demographic characteristics was collected. The skin prick test (SPT) for most prevalent aeroallergens and pulmonary function test (PFT) were performed and the results were clinically matched to investigate the allergic rhinitis (AR) and asthma. Total serum immunoglobulin E (IgE) concentration was analysed in the subjects for the presence of atopy. Results: Ninety one patients (75 of them were females) were enrolled in the study (with a mean age of 36.90 ±12.93 years). SPT result was positive in 75 (82.4%) subjects. Weeds (67 cases, 73.6%), trees (61 cases, 67%), and dust mites (55 cases, 60.4%) were the most common pollens in the positive SPT samples. Thirty-seven (40.7%) of the patients had allergic rhinitis. There was a statistically significant association between the presence of AR and positive SPT result (p = 0.002). Eight patients had allergic asthma and 45 (49.4%) of the patients had a total serum IgE level of more than 100 IU/ml. Conclusions: Our results indicated a clear association between the presence of aeroallergen sensitivity and development of CSU. AR exists as a co-morbidity of CSU.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Medicine Consumptionmentioning

confidence: 99%

Investigating the association of atopy and aeroallergen sensitization and chronic spontaneous urticaria

Esmaeilzadeh¹,

Eskandarisani²,

Nabavizadeh³

et al. 2022

pdia

View full text Add to dashboard Cite

show abstract

“…Another study in children also observed a strong association of urticaria with asthma, eczema, and hay fever [11] . It has been reported that acute urticaria is more common in patients with asthma and could be induced by exacerbation of seasonal asthma [26] . Raciborski et al [12] found that specific foods were important eliciting factors in 12.6% of patients with urticaria.…”

Section: Discussionmentioning

confidence: 95%

Epidemiology of urticaria in China: a population-based study

Mao

Liu

et al. 2022

Chinese Medical Journal

View full text Add to dashboard Cite

Background: Urticaria is a common skin disease characterized by episodes of wheals, and it has a negative effect on patients' quality of life. Large-scale population-based epidemiological studies of urticaria are scarce in China. The aim of this survey was to determine the prevalence, clinical forms, and risk factors of urticaria in the Chinese population. Methods: This survey was conducted in 35 cities from 31 provinces, autonomous regions, and municipalities of China. Two to three communities in each city were selected in this investigation. Participants completed questionnaires and received dermatological examinations. We analyzed the prevalence, clinical forms, and risk factors of urticaria. Results: In total, 44,875 questionnaires were distributed and 41,041 valid questionnaires were collected (17,563 male and 23,478 female participants). The lifetime prevalence of urticaria was 7.30%, with 8.26% in female and 6.34% in male individuals (P < 0.05). The point prevalence of urticaria was 0.75%, with 0.79% in female and 0.71% in male individuals (P < 0.05). Concomitant angioedema was found in 6.16% of patients. Adults had a higher prevalence of urticaria than adolescents and children. Living in urban areas, exposure to pollutants, an anxious or depressed psychological status, a personal and family history of allergy, thyroid diseases, and Helicobacter pylori infection were associated with a higher prevalence of urticaria. Smoking was correlated with a reduced risk of urticaria. Conclusion: This study demonstrated that the lifetime prevalence of urticaria was 7.30% and the point prevalence was 0.75% in the Chinese population; women had a higher prevalence of urticaria than men. Various factors were correlated with urticaria.

show abstract

“…[26][27][28] Some studies have shown that asthma and urticaria are related and that asthma is common in patients with chronic spontaneous urticaria. 29,30 According to previous studies, 4,13 the IV seldomly causes extensive cutaneous or chronic adverse effects. However, the most frequently reported events are injection site transient reactions or nonspecific inflammation.…”

Section: Discussionmentioning

confidence: 97%

<p>Risk Of Urticaria In Geriatric Stroke Patients Who Received Influenza Vaccination: A Retrospective Cohort Study</p>

Lam

Shih

Chen

et al. 2019

CIA

View full text Add to dashboard Cite

Urticaria is a mast cell-related disease caused severe itching and the lifetime prevalence of urticaria is about 20% in general population. Our purpose is to evaluate risk of urticaria in geriatric stroke patients received influenza vaccination (IV). Methods: In a cohort of 192,728 patients with newly diagnosed stroke aged over 65 years obtained from 23 million people in Taiwan's National Health Insurance between 2000 and 2008, we identified 9890 stroke patients who received IV and 9890 propensity score-matched stroke patients who did not receive IV. Controlling for immortal time bias, both the IV and non-IV groups were followed for one year. Urticaria events were identified during the follow-up period. We calculated the adjusted rate ratios (RRs) and 95% confidence intervals (CIs) of the one-year risk of urticaria associated with IV. Results: During the follow-up period of one year, stroke patients with IV had a significantly higher risk of urticaria compared with non-IV stroke patients (RR 1.81, 95% CI 1.47-2.23). An increased risk of urticaria in stroke patients with IV was noted in both sexes, patients 65-84 years of age, patients with comorbid medical conditions, and various time intervals of follow-up. Vaccinated stroke patients with hemorrhage (RR 4.00, 95% CI 1.76-9.10) and those who received intensive care (RR 5.14, 95% CI 2.32-11.4) had a very high risk of urticaria compared with those without IV. Conclusion: Receiving IV may be associated with an increased risk of urticaria in stroke patients. We could not infer the causality from the current results because of this study's limitations. Future investigations are needed to evaluate the possible mechanism underlying the association between IV and urticaria.

show abstract

Seasonal Exacerbation of Asthma Is Frequently Associated with Recurrent Episodes of Acute Urticaria

Cited by 13 publications

References 19 publications

Investigating the association of atopy and aeroallergen sensitization and chronic spontaneous urticaria

Investigating the association of atopy and aeroallergen sensitization and chronic spontaneous urticaria

Epidemiology of urticaria in China: a population-based study

<p>Risk Of Urticaria In Geriatric Stroke Patients Who Received Influenza Vaccination: A Retrospective Cohort Study</p>

Contact Info

Product

Resources

About