Seasonal Reproductive Activity of Male Formosan Wood Mice (Apodemus Semotus): Relationships to Androgen Levels

Lee, C.-Y.; Alexander, P. S.; Yang, V. V. C.; Yu, J. Y.-L.

doi:10.1093/jmammal/82.3.700

Cited by 6 publications

(7 citation statements)

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“…However, in rodents, a state of dominance causes an increase in testis weights (Niehoff et al, 2010). Given that testosterone modulates the expression of BDNF protein and its receptor (Fargo et al, 2009), and that testis mass is an indicator of testosterone level (Lee et al, 2001), we speculate that testosterone might have contributed to the higher serum BDNF levels observed in the EC animals.…”

Section: Discussionmentioning

confidence: 96%

Post‐weaning environmental enrichment improves BDNF response of adult male rats

Mosaferi

Babri

Mohaddes

et al. 2015

Intl J of Devlp Neuroscience

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The environment could have long lasting effects on the individual phenotype through developmental plasticity. Early environmental enrichment exerts profound biological effects, most of which are quite beneficial ones. To explore the enduring effects of rearing condition quality on BDNF(1) responses, we reared male Wistar rats from weaning to young-adulthood in three different environmental conditions: 1. Enriched 2. Standard, and 3. Isolated. Then, at the age of 16 weeks, 10 rats from each group were randomly chosen and allocated to six common mix cages. They were kept together for 14 weeks. At the end of the experiment, each rat received ten inescapable foot-shocks. Twelve hours later, the BDNF contents of the amygdala and CA1 sub-region of the dorsal hippocampus were measured. The serum BDNF levels, hematocrit values as well as brain and testis weights were also measured. Results showed that the environmental enrichment led to stronger dorsal hippocampal BDNF response and higher serum BDNF levels, while rats from standard laboratory condition showed higher amygdala BDNF response. Also, enriched animals showed higher brain weight compared to isolation reared rats as well as higher testis weight and hematocrit value compared to animals reared in standard laboratory condition. Rats showed less body weights in isolated condition. In conclusion, the BDNF profile of enriched animals might represent the neurobiological correlate of resilience phenotype under a stressful situation.

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Section: Discussionmentioning

confidence: 96%

Post‐weaning environmental enrichment improves BDNF response of adult male rats

Mosaferi

Babri

Mohaddes

et al. 2015

Intl J of Devlp Neuroscience

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“…Our recent study showed that Formosan wood mice had higher levels of locomotor activity and exploratory behavioral responses than C57BL/6J mice in a laboratory environment (Shieh and Yang, 2018). Previous studies have also reported that Formosan wood mice show high levels of exploration in the field (Huang et al, 1997;Lee et al, 2001;Lin et al, 1993 maze to examine behavioral responses, jumping-down behavior from open arms during the test was commonly found. Although we excluded the data from mice that showed jumping-down behavior from open arms in the previous study, whether the will of Formosan wood mice to escape could disrupt the findings was unclear.…”

Section: Discussionmentioning

confidence: 78%

“…Some studies have focused on comparisons of the physiological and behavioral responses between wood mice and common laboratory mice (Lejeune et al, 2000;Shieh et al, 2008;Shieh and Yang, 2018;Tosh et al, 2012). The Formosan wood mouse (A. semotus) is an endemic Taiwanese rodent, and most reports related to Formosan wood mice are field studies (Huang et al, 1997;Lee et al, 2001;Lin et al, 1993;Lin and Shiraishi, 1992a,b). Our recent study showed that Formosan wood mice had higher levels of locomotor activity and exploratory behavioral responses than C57BL/6J mice in a laboratory environment (Shieh and Yang, 2018).…”

Section: Discussionmentioning

confidence: 99%

Exploratory and agile behaviors with central dopaminergic activities in open field tests in Formosan wood mice (Apodemus semotus)

Shieh

Yang

2019

Journal of Experimental Biology

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Taiwan is a mountainous island, and nearly 75% of its lands are 1000 m above sea level. Formosan wood mice, Apodemus semotus, are endemic rodents and are broadly distributed at altitudes between 1400 and 3700 m in Taiwan. Interestingly, Formosan wood mice show similar locomotor activity in the laboratory as they do in the wild. Hence, we are interested in studying whether exploratory behaviors and central dopaminergic activity are changed in the open field test. We used male C57BL/6J mice as the control, comparing their behavioral responses in the open field, step-down inhibitory avoidance discrimination and novel object recognition tests with those of male Formosan wood mice. We also examined dopamine and its major metabolite 3,4dihydroxyphenylacetic acid in the medial prefrontal cortex, striatum and nucleus accumbens. In open field tests, Formosan wood mice revealed higher levels of locomotion and exploration than C57BL/6J mice. Learning and memory performance in the novel object recognition test was similar in both Formosan wood mice and C57BL/6J mice, but more agile responses in the inhibitory avoidance discrimination task were found in Formosan wood mice. There was no difference in behavioral responses in the open field test between new second-generation Formosan wood mice and Formosan wood mice that were inbred for more than 10 generations. After repeated exposure to the open field test, high levels of locomotion and exploration as well as central dopaminergic activities were markedly persistent in Formosan wood mice, but these activities were significantly reduced in C57BL/6J mice. Diazepam (anxiolytic) treatment reduced the higher exploratory activity and central dopaminergic activities in Formosan wood mice, but this treatment had no effect in C57BL/6J mice. This study provides comparative findings, as two phylogenetically related species showed differences in behavioral responses.

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“…Many species of Chiroptera share with other mammalian species, some reproductive characteristics that are observed commonly in the temperate species, such as enter into hibernation and present a regression in the seminiferous in which only spermatogonia and Sertoli cells can be observed (Racey, 1974; Fuentes et al, 1991; Lee et al, 2001; Kurohmaru et al, 2002; Lee, 2003; Lee and Mori, 2004). Possibly to adapt to the hibernation period, the mammals species have developed unique characteristics, such as prolonged sperm storage in the cauda epididymis in males and in the oviducts and/or uterine cornua in females, asynchrony between spermatogenesis and the mating period and late ovulation, fertilization and implantation in the female reproductive tract (Anand‐Kumar, 1965; Racey, 1979; Rasweiler, 1993; Crichton and Krutzsch, 2000; Lee et al, 2001; Encarnação et al, 2004; Sharifi et al, 2004, Beguelini et al, 2009, 2011).…”

Section: Discussionmentioning

confidence: 99%

Morphological Variation of Primary Reproductive Structures in Males of Five Families of Neotropical Bats

Beguelini

Puga

Martins

et al. 2012

The Anatomical Record

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Bats present unique features among mammals with respect to reproduction, and although neotropical bats do not have a hibernation period, many of their reproductive characteristics vary seasonally and interspecifically. Thus, this work aimed to examine the reproductive structures of 18 species belonging to five families of Brazilian bats. The gross anatomy of the testes varied little; however, the epididymis of Emballonuridae and Vespertilionidae showed exceptional structures with a large elongation of the caudal region. We observed a wide variation in the positioning of the testes: Phyllostomidae and Noctilionidae presented external testes; Emballonuridae and Molossidae presented migratory testes that may be in intra-abdominal or external positions; and Vespertilionidae displayed scrotal testes. In the histological evaluation, we observed a different pattern in vespertilionid species, with testicular regression and sperm retention/storage in the cauda epididymis in the five species analyzed. Similar testicular regression was observed in Molossops temminckii; however, sperm retention/storage was not observed in this species. These data suggest that although the species analyzed are tropical species that do not present a prolonged period of torpor (hibernation), they still maintain a period of seminiferous tubule regression and sperm storage very similar to that observed in hibernating bats. Anat Rec,

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Seasonal Reproductive Activity of Male Formosan Wood Mice (Apodemus Semotus): Relationships to Androgen Levels

Cited by 6 publications

References 0 publications

Post‐weaning environmental enrichment improves BDNF response of adult male rats

Post‐weaning environmental enrichment improves BDNF response of adult male rats

Exploratory and agile behaviors with central dopaminergic activities in open field tests in Formosan wood mice (Apodemus semotus)

Morphological Variation of Primary Reproductive Structures in Males of Five Families of Neotropical Bats

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