“…The resulting ROS exceed primary scavenging capacity of an organism and attack different cellular components, such as nucleic acids, cytoplasmic proteins, lipids, and membranes (Dröge, 2002;Valavanidis et al, 2006). ROS production in cells, especially in the mitochondria and peroxisome, has been found to be increased in exercised mammalian muscle, stressed bivalve gills, chicken muscles, lugworm and cultured cells as compared with non-stressed control tissue (Keller et al, 2004;Heise et al, 2003). Increase in oxidative process during high concentration of heavy metal or any other pollution related stress causes ROS accumulation, and cellular protection against such damage is achieved mainly by enzymes such as SOD, CAT, GPx or GRd (Lin et al, 2015;Das et al, 2017).…”