Sebaceous Adenoma of the Eyelid in Muir-Torre Syndrome

Singh, Arun D.; Mudhar, Hardeep Singh; Bhola, Ronnie; Rundle, Paul; Rennie, I G

doi:10.1001/archopht.123.4.562

Cited by 27 publications

(7 citation statements)

References 20 publications

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“…If it appears in a young person, it may indicate Muir–Torre syndrome. [ 32 ] Histologically, sebaceous gland adenoma displays similar features to those observed in sebaceous gland hyperplasia.…”

Section: Adnexal Tumors Of the Eyelidmentioning

confidence: 92%

Pathology of eyelid tumors

Pe’er

2016

Indian J Ophthalmol

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The eyelids are composed of four layers: skin and subcutaneous tissue including its adnexa, striated muscle, tarsus with the meibomian glands, and the palpebral conjunctiva. Benign and malignant tumors can arise from each of the eyelid layers. Most eyelid tumors are of cutaneous origin, mostly epidermal, which can be divided into epithelial and melanocytic tumors. Benign epithelial lesions, cystic lesions, and benign melanocytic lesions are very common. The most common malignant eyelid tumors are basal cell carcinoma in Caucasians and sebaceous gland carcinoma in Asians. Adnexal and stromal tumors are less frequent. The present review describes the more important eyelid tumors according to the following groups: Benign and malignant epithelial tumors, benign and malignant melanocytic tumors, benign and malignant adnexal tumors, stromal eyelid tumors, lymphoproliferative and metastatic tumors, other rare eyelid tumors, and inflammatory and infections lesions that simulate neoplasms.

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Section: Adnexal Tumors Of the Eyelidmentioning

confidence: 92%

Pathology of eyelid tumors

Pe’er

2016

Indian J Ophthalmol

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“…This association, known as Muir-Torre Syndrome (MTS), is broadly defined by the presence of sebaceous tumours and internal malignancies in the absence of other predisposing factors 4. Although the most common internal malignancies associated with MTS are colorectal and genitourinary,4 a number of other primary malignancies have also been described 5 6. MTS is inherited in an autosomal dominant pattern and affected patients typically present at an earlier age with malignancy than would be expected in the general population 1…”

Section: Introductionmentioning

confidence: 99%

Sebaceous adenomas of the eyelid and Muir-Torre Syndrome

et al. 2015

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“…(Figure 7) Sebaceous adenoma are often seen as cutaneous component of Muir-Torre syndrome. 16 Our study comprised of only one malignant tumoursebaceous carcinoma which was diagnosed from an eyelid mass of a 68 year male patient. On biopsy, the tumour showed a nesting pattern with cells having finely vacuolated cytoplasm and distinct cell borders.…”

Section: Discussionmentioning

confidence: 99%

Clinico-pathological study of skin adnexal tumours in a tertiary care hospital

Nayak¹,

Raman²,

Rath³

et al. 2020

ACHR

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Background: Skin adnexal tumours are heterogenous group of uncommon tumours having distinct histological features. They have varied clinical presentation and morphological differentiation towards one or more types of adnexal structures found in normal skin. The aim of this study was to study the different histomorphological patterns of appendageal tumours and correlate them with clinical presentations. Materials and Methods: This was a retrospective study of three year duration of all cases clinically diagnosed to be appendageal tumours and confirmed by histopathology in our department. The tumours were classified according to their differentiation after a detailed histopathological examination in haematoxylin and eosin sections. Results: The total number of cases in the study were 43,in which 28 were males and 15 females. Most of the tumours (97.7 %)were benign and there was only one case sebaceous carcinoma. The majority of the tumours had an eccrine differentiation (30.9%), nodular hidradenoma among them being the most common lesion (20.9%). Trichilemmal cyst (30.2%) constituted the maximum cases of pilar origin. Conclusion: Skin adnexal tumours are relatively rare with benign ones being more common than the malignant tumours. Proper clinical correlation and histopathological study helps in reaching a correct diagnosis.

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Sebaceous Adenoma of the Eyelid in Muir-Torre Syndrome

Cited by 27 publications

References 20 publications

Pathology of eyelid tumors

Pathology of eyelid tumors

Sebaceous adenomas of the eyelid and Muir-Torre Syndrome

Clinico-pathological study of skin adnexal tumours in a tertiary care hospital

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