Sebaceous lymphadenoma of the parotid gland

Mishra, Archana; Tripathi, Kalpalata; Mohanty, Lity; Nayak, Manjulata

doi:10.4103/0377-4929.77364

Cited by 8 publications

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“…Sebaceous lymphadenoma (SLA) of the salivary gland is a rare histologic variant of lymphadenoma with sebaceous differentiation or sebaceous adenoma with a dense lymphocytic background . SLA typically occurs in adults over 50 years of age (ranging from 13 to 89) with no predilection toward either sex .…”

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Fine‐needle aspiration cytomorphology of sebaceous lymphadenoma of the salivary gland

Haar

DeFrias

Lin

2013

Diagnostic Cytopathology

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Sebaceous lymphadenoma (SLA) is a histologic variant of lymphadenoma or sebaceous adenoma of the salivary gland. The fine-needle aspiration (FNA) cytology of SLA has not been well-described. In this report, we reported a case that involved an 81-year-old male with a long-standing left parotid mass and was diagnosed on FNA cytology. The FNA smears showed clusters of three types of epithelial cells in a background of abundant lymphoid cells, macrophages and abundant proteinaceous materials. The predominant epithelial cells were large polygonal cells with abundant cytoplasm filled with multiple, uniform, small, and clear vacuoles, ill-defined cytoplasmic borders, and small centrally located round nuclei with finely granular chromatin, conspicuous nucleoli and indented nuclear membranes apparently imprinted by cytoplasmic vacuoles. These cells were surrounded by polygonal or flat cells with less or more dense cytoplasm, indistinct cell borders and round or oval small nuclei with smooth nuclear membranes, which correspond to germinative or basaloid cells. Some cells had granular cytoplasm. Large three dimensional clusters of nonkeratinized squamous cells have oval nuclei containing evenly distributed chromatin, and scant to moderate dense cytoplasm that were arranged in a "stream of fish" pattern. Rare granulomas and cystic contents (degenerated cells, inflammatory cells, macrophages, and abundant granular debris/proteinaceous material) were also seen. The diagnosis of SLA was confirmed by the surgical resection.

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“…The histogenesis of SLA is unclear. There are a couple of hypotheses, which include development within the ectopic salivary gland in intraparotid lymph node, development from branchial clefts, and sebaceous differentiation in other tumors …”

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Fine‐needle aspiration cytomorphology of sebaceous lymphadenoma of the salivary gland

Haar

DeFrias

Lin

2013

Diagnostic Cytopathology

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“…As phenolics and lignification have been associated with plant resistance to a variety of pests and pathogens, investigations have sometimes revealed a correlation of elevated levels of phenolics with resistance or response of plants to nematode infection [101]. Many simple phenols are volatile, and exist in plant essential oils with antinematodal activity.…”

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Secondary Metabolites with Antinematodal Activity from Higher Plants

Zhou¹,

Wang²,

Wang³

et al. 2012

Studies in Natural Products Chemistry

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“…Less than 100 cases have been reported to date [4,5,[21][22][23][24][25]. Patients typically present with a mass, which may be slowly enlarging.…”

Section: Sebaceous and Non-sebaceous Lymphadenomamentioning

confidence: 99%

My Journey into the World of Salivary Gland Sebaceous Neoplasms

Gnepp

2012

Head and Neck Pathol

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As part of this symposium honoring Leon Barnes, the authors were asked to present the case from which they learned the most. I chose a cystic sebaceous lymphadenoma (SL) as my case presentation. This paper presents this unusual case, as well as several additional sebaceous tumors that came across my desk the first few years I was in practice. These interesting cases led me to thoroughly review the literature on sebaceous tumors of the salivary glands, resulting in several publications, the largest series of sebaceous tumors published at this time as well as a careful review of all cases in the literature. The author will also review the current and previous literature on the five types of salivary gland sebaceous tumors: sebaceous adenoma, SL (and non-sebaceous lymphadenoma), sebaceous carcinoma, sebaceous lymphadenocarcinoma, and sebaceous differentiation in other types of salivary gland lesions.

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Sebaceous lymphadenoma of the parotid gland

Cited by 8 publications

References 0 publications

Fine‐needle aspiration cytomorphology of sebaceous lymphadenoma of the salivary gland

Fine‐needle aspiration cytomorphology of sebaceous lymphadenoma of the salivary gland

Secondary Metabolites with Antinematodal Activity from Higher Plants

My Journey into the World of Salivary Gland Sebaceous Neoplasms

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