Secondary cataract: an epidemiologic and clinical survey at the Yaounde Gynaeco-obstetric and Paediatric Hospital

Abstract

Objective:To determine the incidence and risk factors of secondary cataract.Materials and methods:A retrospective study involving a review of medical records in the ophthalmology unit of the Yaoundé Gynaeco-obstetric and Paediatric Hospital in Yaoundé, Cameroon, was carried out. All patients who had cataract surgery between January 2006 and September 2010 were included. Variables included age, sex, past medical history, morphology of primary cataract, type of surgery, intraocular lens implantation, site of implantation, intra- and postoperative complications, and the time lapse for the presentation of secondary cataract. Both univariate and bivariate analyses were carried out. The χ2 test was used to compare proportions, and P-values <0.05 were considered statistically significant.Results:A total of 864 eyes of 718 patients had cataract surgery. Ninety-two eyes developed posterior capsule opacification, giving an incidence of 10.65%. The mean age of patients who developed secondary cataract was 52.3 ± 23.05 years, with a range of 4 years to 84 years. Secondary cataract was more frequent in the age group of 0–20 years. The time lapse for presentation of secondary cataract was 64.7 ± 9.53 days, with a range of 1 to 504 days. Risk factors for the development of secondary cataract were age (P = 0.000), sex (P = 0.011), cortical cataract (P = 0.000), and postoperative inflammation (P = 0.000).Conclusion:The incidence of secondary cataract, though high in this study, is lower than that reported in other studies.

Three-year incidence of Nd:YAG capsulotomy and posterior capsule opacification and its relationship to monofocal acrylic IOL biomaterial: a UK Real World Evidence study

“…These comprised presence of any complications post-surgery, history of co-pathologies (e.g. glaucoma, age-related macular degeneration, diabetic retinopathy) and, to a lesser extent, female gender and younger age, which is congruent with published evidence [ 2 , 28 , 29 ]. It is important to remember, however, that our study restricted the age to 65 years or older so our results are restricted to patients of this age cohort only.…”

Posterior capsule opacification (PCO) rate of a hydrophilic acrylic intraocular lens suitable for microincisional cataract surgery (MICS)

“…We were able to demonstrate a statistically significant correlation between age and PCO rate (p = 0.0001). This statistically significant correlation is also demonstrated by Eballé et al [85]. The PCO rate decreases slightly with age.…”

“…Given that in the literature children and young adults have a higher and faster PCO development [85,86], the statistical evaluations for the group under 55 and the group from 55 or older were carried out separately.…”

Efficient Generation of Lens Progenitor Cells from Cataract Patient–Specific Induced Pluripotent Stem Cells

“…Any disruption to these normal cellular processes can disrupt lens architecture, resulting in cataract formation [4] . Currently, surgery is often the only successful treatment, although this approach it is not without later complications that may lead to what is termed secondary cataract [19] . A common complication following surgery results from the aberrant behavior of the remaining lens cells.…”