Secondary Metabolites from an Algicolous Aspergillus versicolor Strain

Miao, Feng Ping; Li, Xiao Dong; Liu, Xiang Hong; Cichewicz, Robert H.; Ji, Nai Yun

doi:10.3390/md10010131

Cited by 88 publications

(52 citation statements)

References 10 publications

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“…The dye color produced by the fungi was 187 A greyed-purple (Figure 1). Several studies of dyes produced by fungi reported that Aspergillus niger produced brown dyes [13]; yellow dyes were produced by A. terreus [14], A. calidoustus 4BV13 [15], A. versicolor [16] and Aspergillus sp. [17]; Aspergillus sp.…”

Section: Resultsmentioning

confidence: 99%

Coloring Properties Assessment of Dyes Produced by MixedAspergillusandPaecilomyces

Suciatmih

Nurfianti

Magfirani

2018

IOP Conf. Ser.: Earth Environ. Sci.

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Section: Resultsmentioning

confidence: 99%

Coloring Properties Assessment of Dyes Produced by MixedAspergillusandPaecilomyces

Suciatmih

Nurfianti

Magfirani

2018

IOP Conf. Ser.: Earth Environ. Sci.

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“…F18 (isolated from M. guianensis) and Penicillium sp. F3 (from E. precatoria) were cytotoxic in the tests performed against A. salina, and lead to the death of all nauplii within 24 h. Miao et al (2012) found that the substance 6.8-di-O-methylaverufin, produced by an endophytic fungus, showed significant toxicity for A. salina, with CL 50 from 0.5 μg/mL. The lethality of simple organisms such as A. salina has been used for rapid and relatively simple monitoring of biological response (Meyer et al, 1982).…”

Section: Biological Activitiesmentioning

confidence: 96%

Biological activity and production of metabolites from Amazon endophytic fungi

Gurgell¹,

Rodrigues²,

Matias³

et al. 2020

Afr. J. Microbiol. Res.

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Obtaining bioactive metabolites from endophytic microorganisms has become increasingly more interesting in the last few decades, since endophytes are known for their biotechnological potential. However, studies involving endophytic microbiota from tropical hosts are still scarce. In this study, the production of bioactive metabolites from endophytic fungi isolated from Amazonian plants were evaluated. Two fungi (Talaromyces sp. F15 and Aspergillus sp. F18) isolated from Myrcia guianensis (Myrtaceae) and one (Penicillium sp. F3) isolated from Euterpe precatoria (Arecaceae) were analysed. The fungi were cultivated in liquid medium and their metabolites were tested for antimicrobial, antioxidant and cytotoxic activity. Amylase, cellulase and lipase production, as well as biosurfactant production, were also evaluated. The metabolites of Aspergillus sp. F18 showed 69.4% antioxidant activity against DPPH free-radical molecules and cytotoxic activity against A. salina. Penicillium sp. F3 showed cytotoxic activity and stood out as the best amylase producer (31 U/ml). Talaromyces sp. F15 was the best lipase producer (4.5 U/ml) and the best biosurfactant source, with 33.3% emulsification index. These Amazonian host-associated fungi showed biotechnological potential, which are believed should be further investigated in order to elucidate the chemical structure of the metabolites responsible for the activities described here, as well as optimize their production.

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“…Chemical investigation of various algal endophytes yielded a handful of metabolites inhibiting S. aureus as well as E. coli; namely, phenalenone derivatives and scleroderolide [69]; dicerandrol C [48]; brevianamide M, 6,8-di-Omethylaverufin, and 6-O-methylaverufin [70]; isocyathisterol [71]; Z-roquefortine C, viridicatol, penitrem A, and penijanthine A [72]. Manjusha et al [73] testified that the crude extract of endophytic fungus Streptomyces sp.…”

Section: Antibacterial Compoundsmentioning

confidence: 99%

Marine Algicolous Endophytic Fungi - A Promising Drug Resource of the Era

Sarasan

Puthumana

Job

et al. 2017

Journal of Microbiology and Biotechnology

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Endophytic fungi have currently been acknowledged as the most promising source of bioactive compounds for drug discovery, and considerable progress has been made in exploring their diversity, species richness, and bioprospecting. Fungal endophytes from unique environmental settings offer a pool of potentially useful medicinal entities. Owing to the constant stresses imposed on macroalgae by marine environments, it is believed that algae and their associated endophytic symbionts represent a good source of structurally diverse bioactive secondary metabolites. Despite the proven significance of active metabolites of algal endophytes, little have been exploited. This review highlights the latest discoveries in algicolous endophytic research, with particular focus on the bioactive metabolites from algal endophytes. Compounds are classified according to their reported biological activities, like anticancer, antibacterial, antifungal, and antioxidant properties. Present experimental evidence suggests that a majority of the bioactive metabolites were reported from Phaeophyceae followed by Rhodophyceae and Chlorophyceae. An intensive search for newer and more effective bioactive metabolites has generated a treasure trove of publications, and this review partially covers the literature published up to 2016.

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Secondary Metabolites from an Algicolous Aspergillus versicolor Strain

Cited by 88 publications

References 10 publications

Coloring Properties Assessment of Dyes Produced by MixedAspergillusandPaecilomyces

Coloring Properties Assessment of Dyes Produced by MixedAspergillusandPaecilomyces

Biological activity and production of metabolites from Amazon endophytic fungi

Marine Algicolous Endophytic Fungi - A Promising Drug Resource of the Era

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