Secondary metabolites from Opuntia ficus-indica var. saboten

Saleem, Muhammad; Kim, Hyoung Ja; Han, Chang Kyun; Jin, Changbae; Lee, Yong Sup

doi:10.1016/j.phytochem.2006.04.009

Cited by 62 publications

(45 citation statements)

References 24 publications

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“…By comparing the spectroscopic data with the reported literature values, the compounds were identified as (+)-aromadendrin (1), (+)-taxifolin (2), kaempferol (3), kaempferol 3-methyl ether (4), quercetin (5), quercetin 3-methyl ether (6), isorhamnetin (7), isorhamnetin 3-O-β-Dglucopyranoside (8), narcissin (9), benzyl-O-β-D-glucopyranoside (10), picein (11), androsin (12), and 1-Oferuloyl-β-D-glucopyranoside (13), respectively.…”

Section: Resultsmentioning

confidence: 99%

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Phenolic Compounds Isolated fromOpuntia ficus-indicaFruits

Kim

Yang

et al. 2016

Nat Prod Sci

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− On the phytochemical investigation of a 70% ethanol extract of the fruits of Opuntia ficus-indica, (Cacataceae), we could result in the isolation of thirteen phenolic compounds including seven flavonoids (1 -9) and four simple phenolic glycosides (10 -13) by column chromatographic methods. Among the isolated compounds, picein (11), androsin (12), and 1-O-feruloyl-β-D-glucopyranoside (13) were isolated for the first time from O. ficus-indica; additionally, this is the first report benzyl-O-β-D-glucopyranoside (10) from the genus Opuntia. The structures of the compounds were determined by spectral data analysis which included 1D, 2D NMR spectrum and ESIMS.

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Section: Resultsmentioning

confidence: 99%

“…[10][11][12] Among the constituents, phenolic compounds such as flavonoids are known as the most characteristic constituent of the cactus pear. 13 Therefore, this study performed a phytochemical investigation of phenolic compounds from the fruits of O. ficus-indica by various chromatographic methods.…”

Section: -9mentioning

confidence: 99%

Phenolic Compounds Isolated fromOpuntia ficus-indicaFruits

Kim

Yang

et al. 2016

Nat Prod Sci

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“…5). Since both Opuntia species and betanin are well known for their antioxidative activities, 1,6 the level of lipid peroxidation was estimated in the rats pretreated with OFSM or betanin 1 h before WIRS loading. Despite the expectations, only the positive control, Stillen (0.016 nmol/mg protein malondialdehyde), significantly reduced lipid peroxidation induced by WIRS.…”

Section: Effect Of Ofsm and Betanin On The Levels Of Mpo Tnf-a And mentioning

confidence: 99%

“…saboten and is widely cultivated in Jeju Island, Korea, for use in the manufacture of health foods, such as tea, jam, and juice. 5,6 The dried powder of its fruits and stems significantly inhibited HCl-ethanol-, HClaspirin-, and indomethacin-induced gastric lesions in rats without any change in gastric juice secretion. 7,8 Its bioactive chemical constituents include several flavonoids that have been isolated from this plant.…”

Section: Introductionmentioning

confidence: 96%

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Prickly Pear Cactus (Opuntia ficus indicavar.saboten) Protects Against Stress-Induced Acute Gastric Lesions in Rats

Kim

Jeon²,

Kim³

et al. 2012

Journal of Medicinal Food

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The protective activity of prickly pear cactus (Opuntia ficus indica var. saboten) fruit juice and its main constituent, betanin, were evaluated against stress-induced acute gastric lesions in rats. After 6 h of water immersion restraint stress (WIRS), gastric mucosal lesions with bleeding were induced in Sprague-Dawley rats. Pretreatment of a lyophilized powder containing O. ficus indica var. saboten fruit juice and maltodextrin (OFSM) and betanin significantly reduced stress lesions (800-1600 mg/kg). Both OFSM and betanin effectively prevented the decrease in gastric mucus content as detected by alcian blue staining. In addition, OFSM significantly suppressed WIRS-induced increases in the level of gastric mucosal tumor necrosis factor-a and myeloperoxidase (MPO). Betanin alone was only effective in decreasing MPO. These results revealed the protective activity of OFSM against stress-induced acute gastric lesions and that betanin may contribute to OFSM's gastric protective activity, at least in part. When OFSM and betanin were taken together, OFSM exerted gastroprotective activity against stress-induced gastric lesions by maintaining gastric mucus, which might be related to the attenuation of MPOmediated damage and proinflammatory cytokine production.KEY WORDS: betanin gastric lesion Opuntia ficus indica var. saboten water immersion restraint stress

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Assessment of isorhamnetin 3‐O‐neohesperidoside from Acacia salicina: protective effects toward oxidation damage and genotoxicity induced by aflatoxin B1 and nifuroxazide

Bouhlel

Limem

Skandrani

et al. 2010

J of Applied Toxicology

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Antioxidant activity of isorhamnetin 3-O-neohesperidoside, isolated from the leaves of Acacia salicina, was determined by the ability of this compound to inhibit xanthine oxidase activity and to scavenge the free radical 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS(.-)) diammonium salt. Antigenotoxic activity was assessed using the SOS chromotest assay. This compound has the ability to scavenge the ABTS(.+) radical by a hydrogen donating mechanism. We also envisaged the study of the antioxidant effect of this compound by the enzymatic xanthine/xanthine oxidase (X/XOD) assay. Results indicated that isorhamnetin 3-O-neohesperidoside was a potent inhibitor of xanthine oxidase and superoxide anion scavengers. Moreover, this compound induced an inhibitory activity against nifuroxazide and aflatoxine B1 (AFB1) induced genotoxicity. Taken together, these observations provide evidence that isorhamnetin 3-O-neohesperidoside isolated from the leaves of A. salicina is able to protect cells against the consequences of oxidative stress.

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Secondary metabolites from Opuntia ficus-indica var. saboten

Cited by 62 publications

References 24 publications

Phenolic Compounds Isolated fromOpuntia ficus-indicaFruits

Phenolic Compounds Isolated fromOpuntia ficus-indicaFruits

Prickly Pear Cactus (Opuntia ficus indicavar.saboten) Protects Against Stress-Induced Acute Gastric Lesions in Rats

Assessment of isorhamnetin 3‐O‐neohesperidoside from Acacia salicina: protective effects toward oxidation damage and genotoxicity induced by aflatoxin B1 and nifuroxazide

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