Secondary Septicaemia from Intravenous Cannulae

Darrell, J. H.; Garrod, L. P.

doi:10.1136/bmj.2.5655.481

Cited by 39 publications

(7 citation statements)

References 6 publications

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“…Others have recorded an even greater frequency of unintended effects, Gray (1967) reporting that only one third of intravenous infusions were free of some undesired effects and that the latter were strongly related to the duration of treatment. Bacterial contamination of intravenous fluid administrations sets is common (Banks, Yates, Cawdrew, Harris & Kidner, 1970) but septicaemia from this source appears surprisingly rare although Darrell & Garrod (1969) have reported two patients who died following septicaemia arising in this way. No patients developed septicaemia in the present series.…”

Section: Discussionmentioning

confidence: 99%

Intravenous fluids in medical in‐patients.

Lawson¹

1977

Brit J Clinical Pharma

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1 Data from the Boston Collaborative Drug Surveillance Program were reviewed to determine the proportion of patients receiving intravenous fluids in the participating hospitals. 2 Wide differences between hospitals in the United States and four other countries were observed: i.v. fluids being given to 54% of patients in one American hospital and only 7% of patients in an Israeli one. A two‐fold difference in the frequency of i.v. fluid use in two otherwise comparable Scottish teaching hospitals was observed. This difference was not due to observed patient characteristics, did not arise from selection bias or observational differences between the two hospitals and was unlikely to have arisen by chance. 3 It is concluded that the findings were due to different policies on the part of the attending physicians. Although the study could not be used to evaluate the beneficial effects of the administered fluids, adverse effects were common (15% of recipients) and in some instances potentially serious. Adverse effects were reported more frequently after infusion of 5% dextrose (13% of recipients) than after isotonic saline (7%) perhaps because of the low pH of the former solution.

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Section: Discussionmentioning

confidence: 99%

Intravenous fluids in medical in‐patients.

Lawson¹

1977

Brit J Clinical Pharma

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“…However, mixed infections sometimes occur, as illustrated by case 5, in which more than one strain was probably isolated from the blood at different times during life, and also from the valve at necropsy. This may have indicated infection by multiple strains at operation, or superinfection during intravenous treatment (Darrell and Garrod, 1969).…”

Section: Discussionmentioning

confidence: 99%

Coagulase-negative staphylococci causing endocarditis after cardiac surgery

Speller¹,

Mitchell²

1973

J Clin Pathol

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“…Varying reports quote different incidences ofinfection, but certainly unless strict aseptic precautions are used at the time of setting up the central venous line, and good care taken of the catheter site during its time in situ, a high proportion of catheter tips will show signs of infection. All catheter tips should be cultured on removal (Wilmore and Dudrick, 1969;Bolasny et al, 1970;Colvin et al, 1972;Darrell and Garrod, 1969). Henzel and DeWeese (1971) pointed out that the design of some indwelling catheters is such that a portion of the catheter may be accidentally detached as a catheter embolus with dangerous consequences.…”

Section: Discussionmentioning

confidence: 99%