Secondary syphilis with pulmonary involvement

Riganti, Julia; Martin, M.; Torre, Ana Clara; Scalia, Gianluca; Clara, Liliana; Vallone, Marcelo; Galimberti, Ricardo

doi:10.1111/jdv.13483

Cited by 9 publications

(11 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Differential diagnosis for tonsillitis includes infectious mononucleosis and group A streptococcal infection. Pulmonary lesions of syphilis (pulmonary syphilis; PS) have been reported, but rarely [ 5 , 6 , 14 – 16 ]. Coleman proposed clinical criteria for the diagnosis of secondary luetic involvement of the lung [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

“…Coleman proposed clinical criteria for the diagnosis of secondary luetic involvement of the lung [ 17 ]. Patients can either be asymptomatic, as in the present case [ 5 , 6 ], or manifest respiratory symptoms such as dry cough [ 7 ], productive cough [ 15 ], and chest pain [ 14 , 16 ]). Thus, the likelihood of PS could be underestimated without systemic imaging evaluation.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, the likelihood of PS could be underestimated without systemic imaging evaluation. Radiographical images of PS show nodules with/without cavitation [ 5 , 6 , 14 – 16 ], subpleural consolidation [ 7 , 15 ], and interstitial infiltrates [ 6 ]. Bronchial biopsy [ 15 ], percutaneous needle aspiration [ 14 ], and excisional lung biopsy [ 14 , 16 ] are used for diagnosis.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Secondary Syphilis with Tonsillar and Cervical Lymphadenopathy and a Pulmonary Lesion Mimicking Malignant Lymphoma

et al. 2018

View full text Add to dashboard Cite

Patient: Male, 27Final Diagnosis: Secondary syphilisSymptoms: Fever • loss of appetite • neck mass • night sweats • weight lossMedication: Oral amoxicillinClinical Procedure: Lymph node biopsySpecialty: Infectious DiseasesObjective:Challenging differential diagnosisBackground:Syphilis is a sexually transmitted disease caused by the pathogen Treponema pallidum. Prevalence continues to rise, especially among men who have sex with men (MSM). Due to changes in patterns of sexual activity, manifestations of the disease are highly variable.Case Report:A 27-year-old male visited the hospital for a low-grade fever and tender 5-cm mass in the right side of his neck. His right tonsil was swollen and covered with a white coating. Levofloxacin was prescribed, but ineffective. The patient’s levels of liver function enzymes increased gradually. Systemic magnetic resonance imaging (MRI) revealed bilateral cervical lymphadenopathy with right predominance, a right pulmonary nodule, and a periportal lymph node, suggestive of malignant lymphoma. However, a biopsy of the right cervical lymph node showed nonspecific inflammation. Preoperative rapid plasma reagin (RPR) and T. pallidum latex agglutination (TPLA) tests were positive. The patient was MSM and reported oral sex with many sexual partners. A diagnosis of secondary syphilis was made. Oral amoxicillin was effective, and all symptoms other than periportal lymph node resolved.Conclusions:Tonsillitis, cervical lymphadenopathy, and lung lesions can be manifestations of secondary syphilis. A detailed history, pathology, and serology are crucial for diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Secondary Syphilis with Tonsillar and Cervical Lymphadenopathy and a Pulmonary Lesion Mimicking Malignant Lymphoma

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Pulmonary syphilis is rare and there are only 14 cases were reported in the English language literature (7). Radiological presentation included infiltrates and solitary or multiple nodules, sometimes associated with pleural effusion and mimicking malignant lesions (8).…”

Section: Discussionmentioning

confidence: 99%

Primary lung carcinoma combined with pulmonary amyloidosis secondary to syphilis infection

Zhao

Zhang

et al. 2018

J. Thorac. Dis.

View full text Add to dashboard Cite

A 55-year-old female patient was found to have a pulmonary nodule combined with multiple lung cysts detected on CT scan. Video-assisted thoracoscopic surgery (VATS) lobectomy was performed and the nodule showed adenocarcinoma while the whole left upper lobe showed a heavy deposition of amyloid. Syphilis infection was detected and was suspected contributing to secondary pulmonary amyloidosis. Although very rare, pulmonary amyloidosis should be added to the differential diagnosis for solid pulmonary nodules. Furthermore, widespread lung cysts located apart from pulmonary nodules is especially rare in pulmonary amyloidosis secondary to syphilis infection.

show abstract

“…Goldmag particles not only can be coupled with biomolecules such as antibody/ antigen and glycoprotein but also has superparamagnetism which makes it easy to be separated in imposed magnetic field (Chang et al 2015). Syphilis with strong infectivity and large damage is a kind of sexually transmitted disease induced by treponema pallidum (TP) (Riganti et al 2015). Syphilis tends to have an increasingly higher incidence in China, which has been a challenge to public health.…”

Section: Introductionmentioning

confidence: 99%

Application of Goldmag immune probe in timely detection of syphilis based on GIS platform

Zhong

Zhisheng

Nong

et al. 2016

Artificial Cells, Nanomedicine, and Biotechnology

View full text Add to dashboard Cite

The purpose of this study was to apply goldmag immunoprobes into establishment of nanoparticles-based colorimetric assay as well as construction of immunochromatography quantitative and qualitative system by exploring point-of-care testing of syphilis with goldmag particles carrier-based immunoprobe and analysis of spatial data of Geographic Information System (GIS) platform. Goat anti-rabbit immunoglobulin G (IgG) was coupled on the surface of modified nanoparticles, taking N-(3-dimethylaminopropyl)-N'-ethyl-carbodiimide as the connector. Then the nanoparticles were used for colorimetric detection of goat-anti-rabbit IgG in liquid phase system. Based on the analysis of spatial data in GIS platform, we found the probe constructed based on MUA-Fe304/Au nanoparticles responded more sensitive to detection objects compared with the probe designed based on PAA-FeO/Au nanoparticles, and its reaction rate constant was two times that of PAA-FeO/Au nanoparticles based goldmag immunoprobe. Goldmag particles not only can be coupled with biomolecules such as antibody/antigen and glycoprotein but also possess superparamagnetism.

show abstract

Secondary syphilis with pulmonary involvement

Cited by 9 publications

References 8 publications

Secondary Syphilis with Tonsillar and Cervical Lymphadenopathy and a Pulmonary Lesion Mimicking Malignant Lymphoma

Secondary Syphilis with Tonsillar and Cervical Lymphadenopathy and a Pulmonary Lesion Mimicking Malignant Lymphoma

Primary lung carcinoma combined with pulmonary amyloidosis secondary to syphilis infection

Application of Goldmag immune probe in timely detection of syphilis based on GIS platform

Contact Info

Product

Resources

About