Secretory carcinoma of the breast: Results from the survival, epidemiology and end results database

Abstract

Secretory carcinoma of the breast commonly occurs at a later age than previously recognized, and is associated with good long-term survival.

Secretory Carcinoma of Breast in a Patient Treated for Differentiated Thyroid Carcinoma—A Diagnostic Dilemma

“…While long established as a standard therapy for invasive ductal and lobular carcinoma, the role of breast conserving surgery and radiotherapy have not been defined with secretory carcinoma. No chemotherapy data is included in the SEER database; therefore no information on patterns of care regarding chemotherapy use can be determined at present [11,12]. A meta-analysis demonstrated improved breast cancer-specific survival with the addition of radiation therapy to breast conserving surgery in invasive carcinoma breast, at the expense of increased non-breast cancer-specific mortality [13].…”

Pediatric and Adolescent Breast Masses: A Review of Pathophysiology, Imaging, Diagnosis, and Treatment

“…The tumor most frequently reported in the literature is secretory carcinoma, which is less aggressive than infiltrating ductal carcinoma, though it does possess malignant potential and can recur locally and metastasize to axillary nodes. A recent review of Surveillance, Epidemiology and End Results data [37] included secretory carcinomas in patients ranging in age from 11 to 86 years and noted a 5-year overall survival of 87.2%, with no deaths reported among the patients treated with lumpectomy and radiation therapy. Clinically, secretory carcinoma of the pediatric breast presents as a firm and immobile painless enlarging mass [38].…”

How to approach breast lesions in children and adolescents

“…The most common subtype of invasive breast cancer in children is invasive secretory carcinoma, which carries a more favorable prognosis as compared to the less common subtypes of breast cancer seen in children (invasive ductal, invasive lobular, medullary, inflammatory, and anaplastic carcinomas) [5,50,51]. Secretory carcinomas are small circumscribed masses (usually < 3 cm) that present as painless palpable masses (Fig.…”