Sedation Depends on the Extension of Sensory Block Induced by Spinal Anesthesia

Gentili, M; Huu, Phu; Enel, Dominique; Hollande, J.; Bonnet, Francis

doi:10.1097/00000542-199809150-00035

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2009

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“…The effect of intravenous administration of midazolam with ketamine specifically on spinal block has not been studied before, but it has been previously shown that increased sedation has been associated with high spinal block 20 It has also been demonstrated that high spinal anesthesia increased sensitivity to the sedative effect of midazolam 21–23 . Although statistically not significant in the current study, the sensory and motor blocks were intensified in the ketamine + midazolam group.…”

Section: Discussioncontrasting

confidence: 58%

Effects of Intravenous Small Dose Ketamine and Midazolam on Postoperative Pain Following Knee Arthroscopy

Akkurt¹,

İnanoğlu²,

Kalacı

et al. 2009

Pain Practice

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Ketamine improved the postoperative pain patient satisfaction, increased the maximal sensory level, and was associated with lower sedation scores in the first 15 minutes after administration. Group I was also associated with decreased total meperidine consumption and delayed the time to first recue analgesic administration. Coadministration of ketamine and midazolam did not provide any further benefit over ketamine alone.

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Section: Discussioncontrasting

confidence: 58%