12Soybean is a crop of major economic importance with low rates of genetic gains for grain yield 13 compared to other field crops. A deeper understanding of the genetic architecture of yield 14 components may enable better ways to tackle the breeding challenges. Key yield components 15 include the total number of pods, nodes and the ratio pods per node. We evaluated the SoyNAM 16 population, containing approximately 5600 lines from 40 biparental families that share a common 17 parent, in 6 environments distributed across 3 years. The study indicates that the yield components 18 under evaluation have low heritability, a reasonable amount of epistatic control, and partially 19 oligogenic architecture: 18 quantitative trait loci were identified across the three yield components 20 using multi-approach signal detection. Genetic correlation between yield and yield components was 21 highly variable from family-to-family, ranging from -0.2 to 0.5. The genotype-by-environment 22 correlation of yield components ranged from -0.1 to 0.4 within families. The number of pods can be 23 utilized for indirect selection of yield. The selection of soybean for enhanced yield components can 24 be successfully performed via genomic prediction, but the challenging data collections necessary to 25 recalibrate models over time makes the introgression of QTLs a potentially more feasible breeding 26 strategy. The genomic prediction of yield components was relatively accurate across families, but 27 less accurate predictions were obtained from within-family predictions and predicting families not 28 observed included in the calibration set. 29 30 Introduction 31 32Soybean is a field crop of major importance due to its seed composition, containing approximately 33 40% protein and 20% oil. Soybean has restricted genetic basis (Mikel et al. 2010) and the rate of 34