Seftarolin, Antibiotik Baru dengan Aktivitas Anti-MRSA: Sebuah Kajian Efektivitas, Keamanan, dan Biaya Penggunaan

Abstract

A growing problem in the medical field is the development of antibiotic resistant pathogens. One reason this development is so important is that in recent years there is a shortage of new antibiotics in development to combat resistant pathogens. It worths to mention that while 19 new antibiotics were released in the period 1980 to 1984, this had dropped to just three in the period 2005 to 2009. Ironically, the shortage of new antibiotics occur in the era where growing number of pathogens develop resistance to multiple antibiotics that previously effectively used to treat the infections. As a consequent, it is essential that the efficacy of last resort antibiotics, including the new antibiotics, be maintained as long as possible. Ceftaroline is a new antibiotic in Indonesia market which has methicillin-resistant Staphylococcus aureus activity and it belongs to the cephalosporins. Further understanding related to basic profile of ceftaroline, efficacy and safety, cost, and place in therapy is needed to optimize the responsible used of ceftaroline in daily medical practice

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Quantitative Analysis of Medication Management and Use in Bima Regional Public Hospital

“…Admittedly, there are several barriers to quality management and use of medications one of which is the development of new medications (17). Hence, Medicines Management teams in hospitals should always take into consideration the potential new medications, including antibiotics, which is about to be introduced in Indonesian market (18).…”

Aktifitas Antibiotik Ceftazidime-Avibactam Dan Ceftaroline Secara In Vitro Terhadap Isolat Klinis Di Pekanbaru

“…Oleh karena itu, keberadaan antibiotik dengan aktivitas anti-MRSA lain seperti ceftaroline dibutuhkan sebagai alternatif terapi untuk kasus yang tidak dapat teratasi oleh beberapa antibiotik yang saat ini terdapat di Indonesia. 7 Antibiotik ceftaroline adalah antibiotik golongan sefalosporin baru (generasi ke-5) yang diindikasikan untuk acute bacterial skin and skin structure infections (ABSSI) yang disebabkan oleh methicillin-resistant staphylococcus aureus (MRSA) dan community-acquired bacterial pneumonia (CABP) yang disebabkan oleh Streptococcus pneumoniae dan bakteri lain yang peka, untuk anak berumur 2 bulan atau lebih. Ceftaroline juga memiliki efek antibakteri terhadap bakteri batang Gram negatif termasuk H. influenzae, Klebsiella sp dan Escherichia coli.…”