Seguimiento clínico y factores de riesgo en niños con enfermedades respiratorias por adenovirus

P, María José Pérez; A, Ricardo Kogan; C, Leonardo Maggi; N, Carmen Mendoza

doi:10.4067/s0370-41062007000300004

Cited by 6 publications

(3 citation statements)

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“…The M/F ratio found in our population was 1.3, an interesting finding noted by others. Studies from Colombia, Chile, Argentina, Brazil, and Cuba found a significantly higher M/F ratio, 2.3 [38] , 1.5 [44] and 2.2 [47] , 1.8 [48] , 1.5 [49] , and 2.0 [45] , respectively. Other authors in USA, Spain, Taiwan, and Israel also found high M/F ratios, 1.4 [50] , 1.5 [25] , 1.6 [51] , and 1.5 [52] , respectively.…”

Section: Discussionmentioning

confidence: 99%

Adenovirus Respiratory Tract Infections in Peru

Ampuero

Ocaña²,

Gómez

et al. 2012

PLoS ONE

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BackgroundCurrently, there is a paucity of data regarding human adenovirus (HAdv) circulation in Andean regions of South America. To address this shortcoming, we report the clinical, phylogenetic, and epidemiologic characteristics of HAdv respiratory tract infection from a large sentinel surveillance study conducted among adults and children in Peru.Methods/Principal FindingsOropharyngeal swabs were collected from participants visiting any of 38 participating health centers, and viral pathogens were identified by immunofluorescence assay in cell culture. In addition, molecular characterization was performed on 226 randomly selected HAdv samples. Between 2000 and 2010, a total of 26,375 participants with influenza-like illness (ILI) or severe acute respiratory infection (SARI) were enrolled in the study. HAdv infection was identified in 2.5% of cases and represented 6.2% of all viral pathogens. Co-infection with a heterologous virus was found in 15.5% of HAdv cases. HAdv infection was largely confined to children under the age of 15, representing 88.6% of HAdv cases identified. No clinical characteristics were found to significantly distinguish HAdv infection from other respiratory viruses. Geographically, HAdv infections were more common in sites from the arid coastal regions than in the jungle or highland regions. Co-circulation of subgroups B and C was observed each year between 2006 and 2010, but no clear seasonal patterns of transmission were detected.Conclusions/SignificanceHAdv accounted for a significant fraction of those presenting with ILI and SARI in Peru and tended to affect the younger population disproportionately. Longitudinal studies will help better characterize the clinical course of patients with HAdv in Peru, as well as determine the role of co-infections in the evolution of illness.

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Section: Discussionmentioning

confidence: 99%

Adenovirus Respiratory Tract Infections in Peru

Ampuero

Ocaña²,

Gómez

et al. 2012

PLoS ONE

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“…48 En este sentido son factores de riesgo: edad menor de 12 meses, antecedente de hospitalización reciente por infección del tracto respiratorio inferior, inmunodeficiencia subyacente, antecedentes de neumonía o asma e infección nosocomial por adenovirus. 49,50 En países endémi-cos también destacan las micobacterias (M. tuber-culosis y micobacterias atípicas). 29 Es importante tener presente la bronquitis bacteriana persistente como causa de bronquiectasias.…”

Section: Inmunodeficienciasunclassified

Bronquiectasias en pediatría, aproximación diagnóstica y tratamiento

et al. 2012

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RESUMENLas bronquiectasias son un problema de salud en países desarrollados y en vías de desarrollo. La fibrosis quística es una causa importante, si bien fuera de ésta existen causas que convierten a las bronquiectasias no relacionadas con fibrosis quística en un diagnóstico frecuente. Su diagnóstico precoz basado en la clínica y posterior confirmación radiológica es el punto de partida para determinar la etiología e instaurar un tratamiento dirigido a la causa subyacente. Para ello es menester una evaluación ordenada y sistemá-tica. Se presenta una revisión sobre la etiología y tratamiento de las bronquiectasias, especialmente de las no relacionadas con fibrosis quística. Palabras clave: bronquiectasias, fibrosis quística, antibióticos, infección bronquial, diagnóstico. SUMMARYBronchiectasis is still an important health problem in both, developed and developing countries. Cystic fibrosis is one of the most important causes, but a great variety of other causes makes non cystic fibrosis bronchiectasis a relatively frequent diagnosis. Early diagnosis based on medical history and radiological confirmation is only the starting point to determine the specific etiology, in order to establish a treatment focused on the underlying cause. For this purpose, an orderly and systematic diagnostic evaluation is required. A review article about bronchiectasis, particularly those not related to cystic fibrosis, is presented.

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“…La literatura médica reporta frecuencias entre 1 y 24% en hospitales pediátri-cos [1][2][3][4] , y se han asociado a mayor morbi-mortalidad y a un aumento de los costos en salud [5][6][7][8][9][10] . Las IAAS representan además un indicador de la calidad de la atención hospitalaria, y está demostrado que las medidas de vigilancia y programas de control permiten reducir en forma muy importante la incidencia de este tipo de infecciones 4,11 .…”

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