In order to determine the calculational model of long span transmission tower structure under the multiple support excitation, tower-lines system are adopted. Seismic Performance of long span transmission tower lines system under Multiple Support Excitation were studied by time history analysis method. The seismic response difference of two kinds of excitation is analyzed from Dynamic Characteristics and the number of dangerous bar. It will offer the theory data for the seismic design of the kind of structure. Through analysis, the seismic response difference of the two kinds excitation is correlative to the apparent velocity; Therefore long span transmission tower structure should be considered the effect of multiple support excitation, otherwise the conclusion will be inclined to conservative or risk. Key words: tower lines system; seismic response; time history analysis,multiple support excitation