Seizures associated with stroke in childhood

Yang, Jae Seung; Park, Yong D.; Hartlage, Patricia L.

doi:10.1016/0887-8994(94)00152-r

Cited by 65 publications

(56 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Morais et al (5) and Yang et al (14) found a significant association between late post-stroke seizures and epilepsy in children after ischemic stroke similar to our study. These studies agree that late post-stroke seizure was a risk factor for post-stroke epilepsy.…”

Section: Epilepsysupporting

confidence: 81%

Risk factors for epilepsy after ischemic stroke in children

İncecik¹,

Hergüner²,

Beşen³

2017

BUCH

View full text Add to dashboard Cite

Objective: We performed this study to determine the incidence of seizures and poststroke epilepsy and risk factors of post-stroke epilepsy after childhood ischemic stroke. Methods: In this study, we retrospectively analyzed data from children who had ischemic stroke. Results: Of the one hundred and two children, mean age of stroke onset was 67.32± 25.48 months (1-180 months). There were 56 (54.9%) boys and 46 (45.1%) girls in the study . Of the 102 patients, 39 (38.2%) had seizures. Twenty seven (69.2%) had earlyonset post-stroke seizures, and 12 (30.8%) had late-onset post-stroke seizures. Epilepsy were detected in 17 (16.7%) of the patients. Eight of them had early-onset and nine had late-onset post-stroke seizures. We found that cortical involvement and late onset post-stroke seizure are predictors of the development of post-stroke epilepsy. Conclusions: Post-stroke seizures and epilepsy in children are common. Therefore, further studies are needed to describe risk factors for the development of post-stroke epilepsy in this population. Keywords:Ischemic stroke, post-stroke epilepsy, risk factors, children ÖZ Amaç: Bu çalışma, çocukluk çağı iskemik inme sonrasında nöbet, epilepsi ve epilepsi insidansı ile risk faktörlerinin saptanması için yapıldı. Yöntem: Çalışmada, iskemik inme geçiren çocukların verileri retrospektif olarak analiz edildi. Bulgular: İskemik inme geçiren 102 hastanın yaş ortalaması 67,32± 25,48 ay (1-180 ay) idi. Elli altısı (%54,9) erkek ve 46'sı ise (%45,1) kız idi. Yüz iki hastanın, 39'u (%38,2) nöbet geçirmişti. Yirmi yedi (%69,2) hastanın nöbeti erken başlangıçlı iken, 12 (%30,8) hastanın nöbeti geç başlangıçlıydı. Hastaların 17'sinde (%16,7) epilepsi gelişmişti. Bunların 8'i erken başlangıçlı nöbeti olan hastayken, 9'u ise geç başlangıç-lı nöbeti olan hastalardı. Lezyonun lokalizasyonu ve nöbet başlama zamanı epilepsi için risk faktörü saptandı. Sonuç: İnme sonrası nöbetler ve epilepsi çocuklarda sık görülür. Bu nedenle, bu populasyonda, inme sonrası epilepsi gelişme riskini saptamak için daha fazla çalışma-ya gereksinim vardır.

show abstract

Section: Epilepsysupporting

confidence: 81%

Risk factors for epilepsy after ischemic stroke in children

İncecik¹,

Hergüner²,

Beşen³

2017

BUCH

View full text Add to dashboard Cite

show abstract

“…Giroud e col. 1 encontraram prevalência de 35% em crianças com acidente vascular cerebral isquêmico (AVCI) e 39% em crianças com acidente vascular cerebral hemorrágico (AVCH). Yang e col. 4 apresentam prevalência de 49,3% em um grupo de pacientes abaixo de 17 anos de idade. Entretanto, estudos realizados em populações de adultos sugerem, na fase aguda, incidência entre 2,4% a 5,4% [5][6][7] .…”

Section: Discussão Discussão Discussão Discussão Discussãounclassified

“…A Tabela 5 mostra a distribuição da localização da DCV nos grupos 1 e 2, nos quais o envolvimento cortical evidenciado pela neuroimagem é fator estatisticamente significante (p=0,0101) na ocorrência de manifestação epiléptica associada à DCV, o que está de acordo com os achados da literatura [4][5][6]10 . Apesar de menos frequente, a manifestação epiléptica pode estar associada a DCV subcortical, algumas vezes porque uma lesão cortical adjacente não foi demonstrada na tomografia de crânio, ou ainda porque a lesão, como por exemplo na cabeça do núcleo caudado, pode apresentar atividade epileptiforme 7,11 .…”

Section: Discussão Discussão Discussão Discussão Discussãounclassified

Doença cerebrovascular na infância: I. Manifestações epilépticas

Montenegro¹,

Guerreiro

Scotoni

et al. 1999

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

RESUMO -As crises epilépticas podem constituir complicação de doença cerebrovascular (DCV), e a sua prevalência, apresentação clínica, fatores de risco e evolução em crianças tem sido estudadas por poucos autores. Neste estudo, 39 crianças com diagnóstico de DCV foram avaliadas quanto à ocorrência de manifestações epilépticas. Vinte e quatro (61,5%) apresentaram crises durante algum momento da doença (22 na fase aguda e 2 na tardia); 13 (54,2%) apresentaram crises generalizadas, 7 (29,2%) parciais, e 4 (16,6%) secundariamente generalizadas. A prevalência de manifestação epiléptica em lactentes foi significativamente maior (p=0,0362) do que nas outras faixas etárias. A localização cortical da DCV mostrou determinar de modo estatisticamente significante (p=0,0101) a ocorrência de crises. Não houve relação significativa entre o tipo de insulto vascular (isquêmico ou hemorrágico) e a ocorrência de crises. Quatorze pacientes evoluíram sem crise após a fase aguda; os 2 pacientes previamente epilépticos tiveram suas crises controladas com droga anti-epiléptica (DAE); 3 evoluíram com epilepsia (1 controlado com DAE e 2 de difícil controle); 3 continuaram em acompanhamento ambulatorial e não houve tempo hábil para definir se o quadro evoluirá para epilepsia e em 2 ocorreu óbito na fase aguda. PALAVRAS-CHAVE: epilepsia, doença cerebrovascular aguda, infância. Cerebrovascular disease in children: I. Epileptic manifestationsABSTRACT -Seizures may occur as a complication of cerebrovascular disease (CVD) and its prevalence, clinical presentation, risk factors and evolution have been reported by few authors. We evaluated 39 children with CVD and analysed the association with seizures. Seizures occurred in 24 (61.5%) patients and were classified as partial (29.2%), generalized (54.2%) and secondarily generalized (16.6%). Infants had a significantly higher prevalence of seizures (p=0.0362) than children at other ages. Cortical localization was associated with a significantly higher prevalence of seizures (p=0.0101). There were no differences between ischemic and hemorrhagic strokes. Fourteen patients had no seizures after the acute phase of the CVD, the 2 previously epileptic patients had their seizures controled with antiepileptic drugs, 3 developed epilepsy, 2 died during the acute phase and in 3 patients there was not enough time yet to make a clear diagnosis of epilepsy.

show abstract

“…It is known that the incidence of seizures after stroke is much higher in children than in adults. Furthermore, in children, as opposed to adults, most seizures associated with stroke occur within the first 24 hours (Yang et al 1995, Bladin et al 2000. We suggest that cerebral imaging to exclude stroke as a potential cause should be considered in children with persistent postictal focal neurological deficits disproportionate to the severity and duration of the initial seizure, particularly in those who were not previously diagnosed with epilepsy.…”

Section: Primary Stroke Diagnosismentioning

confidence: 99%

Diagnostic pitfalls in paediatric ischaemic stroke

Braun¹,

Kappelle

Kirkham

et al. 2006

Develop Med Child Neuro

View full text Add to dashboard Cite

Diagnosing ischaemic stroke and determining its cause is difficult in children. Both are important for selection of treatment and prediction of outcome. This study explored the diagnostic changes that lead to a delay in the correct diagnosis of paediatric stroke. Case histories of 45 children with ischaemic stroke (31 males, 14 females; median age 6y; age range 2mo–16y) were retrospectively reviewed. The initial clinical diagnosis, based on the interpretation of presenting symptoms, was compared with the final aetiological stroke diagnosis after completion and review of diagnostic work‐up. The type of diagnostic change, consequent time delay until correct diagnosis, reasons for change of diagnosis, and alterations to management were evaluated. Twenty‐four diagnostic changes were identified; 19 in ‘primary stroke diagnosis’ (symptoms initially not attributed to stroke), and five in ‘aetiological diagnosis’ (incorrect initial determination of type or cause of stroke). The median interval between initial and final diagnosis was 7 days (3h–2y). The change in diagnosis led to therapeutic alterations in 17 patients. Risk factors for childhood stroke differ from those in adults. Stroke is frequently not recognized as the cause of the child's symptoms, and the correct determination of stroke aetiology takes time. We recommend that children with stroke be evaluated in a centre with expertize, using standardized diagnostic protocols and careful follow‐up.

show abstract

Seizures associated with stroke in childhood

Cited by 65 publications

References 22 publications

Risk factors for epilepsy after ischemic stroke in children

Risk factors for epilepsy after ischemic stroke in children

Doença cerebrovascular na infância: I. Manifestações epilépticas

Diagnostic pitfalls in paediatric ischaemic stroke

Contact Info

Product

Resources

About