Seleção de córneas para transplantes

Abstract

RESUMOO transplante de córnea é singular, pelo fato de ser habitualmente realizado em pessoas com deficiência visual, mas com expectativa de vida, mobilidade e convivência social preservadas. Um enxerto mal-sucedido pode levar à cegueira real ou ao sofrimento permanente, motivado por dor ou desconforto ocular. Um dos fatores fundamentais do sucesso do mesmo é o uso de córneas de boa qualidade. A seleção dessas córneas assenta-se em três princípios: inocuidade, transparência e vitalidade. Cada um deles é analisado detalhadamente neste trabalho.Descritores: Transplante de córnea; Preservação de órgãos; Doadores de tecidos; Seleção do doador; Coleta de tecidos e órgãos; Controle de qualidade ABSTRACTCorneal transplantation is singular because it is habitually performed on persons with visual deficiency but with preserved life expectancy, mobility and social life. A graft not well succeeded may cause real blindness and permanent misery due to pain and discomfort. One of the fundamental determinants of the success of corneal transplantation is the use of corneas of good quality. The selection of these corneas is based on three rules: innocuousness, transparency and vitality. Each one of these concepts is considered in detail in this work.

Epidemiological profile of west center cornea donors

“…However, the time of both periods was higher than the one in other studies (9,17) . Although higher, this value is within the limit of six hours between death and enucleation (6,(18)(19)(20) , whereas another study shows that enucleation may be placed within 24 hours if the body is cooled (21) . In our study the cornea was preserved for a maximum of 14 days of preservation, which was also found in other (1,18,21,22) .…”

Donor selection criteria: In Vitro Corneal Analysis

“…These voids appear as dark or grayish spots distributed in two basic patterns: focal and linear ( Figure 3) 23 . They are spread randomly along the endothelial mosaic.…”

Characteristics of corneal donations in state of Piauí

“…It is believed that the degradation of ocular contentsafter the donor's death can alter the aqueous humour, accelerating the death of endothelial cells 14 . This suggests that the faster the eye is removed from the body, and the faster the cornea is removed from the eye, the lower the chance of endothelial intoxication.…”

“…However, the practical importance of this phenomenon remains unclear 14 . In our study,the preservation time for optical corneas was significantly lower than for tectonic corneas, similar to other studies 12,13 , showing the need for swift processes in eye banks, as the vitality and quality of tissues are also dependent on time.…”