Work in the context of the COVID-19 pandemic has shown that all medical activities should be aimed at preventing infectious risks, the presence of which often leads to the development of emergency situations. The purpose of this work was to analyze the frequency of epidemic risks in the work of the endoscopic service of the pulmonological center. The recorded epidemic risks during endoscopic examinations in the endoscopic office of the Samara City Hospital No. 4 (on the basis of which the City Pulmonological Center is deployed) for the period from 06/10/2022 have been analyzed. by 05/19/2023 Endoscopic examinations were performed both in the endoscopic office of the hospital and in the intensive care unit. During the reporting period, 1,903 endoscopic examinations (100 %) were performed, including 1,479 bronchoscopy (77.7 %) and 424 esophagogastroduodenoscopy (EGDS) (22.3 %). A total of 273 cases of endoscopic interventions associated with epidemic risks were identified, which amounted to 14.32 % of the total number of studies. HIV infection was detected in a total of 204 patients, which was 10.7 % per 100 endoscopic examinations performed. The second most common was the risk of hepatitis C virus infection in 99 patients (5.2 %), the third was tuberculosis (32 people, 1.7 %). Thus, the conducted research made it possible to assess the risks of infection of medical personnel during endoscopic examinations, the most significant of which is infection with HIV, hepatitis C virus and tuberculosis pathogens.