Selection of additive manufacturing technologies in productive systems: a decision support model

Calderaro, Douglas Rhoden; Lacerda, Daniel Pacheco; Veit, Douglas Rafael

doi:10.1590/0104-530x5363-20

Cited by 16 publications

(4 citation statements)

References 71 publications

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“…-минимизации государственного контроля и отсутствию жестких регламентирующих документов (что только ускоряет распространение технологий и дальнейшее экспериментирование) (Calderaro, Lacerda & Veit, 2020).…”

Section: стратегии развития аддитивных технологий и их нормативная ос...unclassified

Legal regulation of additive technologies in modern biomedicine

Romanovskaya

Romanovsky

2023

Vestn. Ross. univ. družby nar., Ser. Ûrid. nauki

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Research reveals the legal problems that arise due to the rapid pace of development of additive technologies (3D printing) in biomedicine (bioprinting). The purpose of the research is to analyze the legislation that defines the legal regime of additive technologies, identify the main gaps in regulation, carry out a comparative legal study, which allows to formulate recommendations to improve Russian legislation. Special strategies are used as an object of comparative research; they contribute to fix the priority development of 3D printing. The employed methods are as follows: the method of analysis of legal regulation, comparative legal and formal legal. Results. Attention is paid to the main trends and risks of progress in this direction, which are reflected in decentralization of production; improving its efficiency and reducing waste; reduction of development time and their introduction into mass production with a simultaneous rise in quality of the finished product; expanding the population's access to material goods; minimizing the state control. Particular attention is paid to the legal assessment of the applicability of bioprinting in transplantology, the manufacture of implants, surgical planning, and the use of printed organs for experiments. Conclusions: when adjusting the legal framework, institutional readiness should be taken into account - the ability of the entire Russian healthcare system to use additive technologies properly (which will require significant changes in healthcare legislation). An independent direction is the use of bioprinting in the testing of drugs. 3D printing creates small organ-like structures (they are called organoids) on which experiments can be carried out for the screening of pharmaceuticals. This will require changes in the legal regime for the circulation of medicines, as well as the main functions of the state regulator (the Russian Ministry of Health and Roszdravnadzor). It is noted that additive technologies make it possible to manufacture medicines, but world experience indicates a cautious attitude towards this type of production. Research argues for the need to follow a risk-based approach in the legal regulation of bioprinting, as well as to introduce the general approach of Hospital Exemption (pharmaceutical exclusion) used in the countries of the European Union, as well as some other countries aimed at the development of regenerative medicine.

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Section: стратегии развития аддитивных технологий и их нормативная ос...unclassified

Legal regulation of additive technologies in modern biomedicine

Romanovskaya

Romanovsky

2023

Vestn. Ross. univ. družby nar., Ser. Ûrid. nauki

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“…The thermal stress can be released by rising the temperature of the process However, the following risks associate with EBM also need to be considered: Given the availability of technologies that make it possible to obtain optimized blade fin geometries, an appropriate selection of material needs to be considered. Titanium, nickel and chrome-cobalt alloys can be used in the EBM process [26]. The benefits of titanium alloys over nickel alloys were already summarized in Section 2.1.…”

Section: Additive Manufacturing 231 Printingmentioning

confidence: 99%

Feasibility Study of Fluidic Sealing in Turbine Shroud

et al. 2021

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This paper analyses the methods for manufacturing turbine blades, focusing on the possibility of manufacturing slots in the region of the shroud. The reason for this analysis is the new flow control technique that can be used to limit the shroud leakage flow in a turbine—the air curtain. The air curtain uses a bypass slot to connect the upstream cavern of a shroud seal with the tip of a shroud fin. The bypass slot is an essential part of the solution, while at the same time introducing difficulties in the manufacturing process. Additionally, a parametric study on the bypass slot dimensions is performed using numerical simulations. The features of the numerical model and its validation against experimental data are presented. The parametric study includes the inlet and outlet dimensions, as well as the width of the slot. The most effective dimensions are shown, along with a possible explanation as to why they are the most effective. Interestingly, a slot that does not cover the whole span of the fin is more effective than a slot covering the whole span of the fin. This is caused by additional streamwise vortices that are created in the proximity of the bypass slot.

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“…Moreover, the other challenges include: (i) size limitations [1], [15], (ii) quality consistency [16], (iii) scaling issues [17], [18] and (iv) high material cost [16], [18], [19]. In this context, there are mainly two parameters: (i) Process parameter which primarily influences material processing during AM and (ii) Structural parameter which provides a 'post-mortem analysis' in terms of microstructural features of AM products and hence, is very essential in selection of materials for AM [20]. Optimisation of these two parameters is extremely necessary for overcoming the aforementioned challenges associated with AM [21]- [40].…”

Section: Introductionmentioning

confidence: 99%