Selection of an Alternate Biocide for the ISS Internal Thermal Control System Coolant - Phase II

Wetting/spreading on porous media and on deformable, soluble structured substrates as a model system for studying the effect of morphology on biofilms wetting and for assessing anti-biofilm methods

“…Onboard the International Space Station (ISS) biofilm formation [26] and consequently microbial contamination continues to pose mission risks, to crew wellbeing as the opportunistic pathogens in water systems and crew cabin present a serious health threat [27][28][29][30]. On the other hand, formation of biofilms on mechanical systems can seriously challenge the hardware reliability as they can also cause biofouling and material degradation, which can lead to system failure during long term missions [31][32][33]. Especially, that with increasing spacecraft complexity, crew numbers, duration of missions, and multiple flights for each spacecraft, new challenges have arisen for long-term control of microbial contamination and biofilm development in systems reused mission-to-mission, particularly in the water storage/distribution systems [28].…”

ISS Internal Active Thermal Control System (IATCS) Coolant Remediation Project

“…The first comprehensive program to competitively evaluate as many options as possible has been well documented and published [Ill, [12]. This effort led to the selection of glutaraldehyde at a use concentration of 250 ppm.…”