Selection of Antimicrobial Agents by Laboratory Means

Spaulding, Earle H.; Anderson, Tara

doi:10.1001/jama.1951.03670310026010

Cited by 19 publications

(3 citation statements)

References 12 publications

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“…Vancomycin, the tetracyclines, streptomycin, nystatin, dihydrostreptomycin, and furadantin have also been shown to be affected by agar (10,16,17,29). In some instances, bacteria that appear resistant to antibiotics by evaluation with sensitivity discs may be rapidly destroyed by the antibiotic in vivo (27).…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Activity in the Presence of Agar

Hanus

Sands

Bennett

1967

Applied Microbiology

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Section: Discussionmentioning

confidence: 99%

Antibiotic Activity in the Presence of Agar

Hanus

Sands

Bennett

1967

Applied Microbiology

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“…Because the single disk method has been shown to be a useful and reliable technique for testing the antimicrobial susceptibility of socalled rapidly growing pathogens (5,6,9,10,12,20,25,28) (21). Briefly, this involved use of indophenol oxidase production, motility, pigment production, fluorescence, denitrification, and resistance to a 2-U penicillin disk.…”

mentioning

confidence: 99%

Antibiotic Susceptibility Testing of Gram-Negative Nonfermentative Bacilli

Ruddell

Anselmo

1975

Antimicrob Agents Chemother

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A study was undertaken to determine if current methods of antibiotic susceptibility testing could be successfully applied to the gram-negative nonfermentative bacilli. Using clinical isolates and reference strains, experiments were conducted on the inherent reliability of the Bauer-Kirby method, as well as the .effect of certain modifications on the method such as elimination of the 2-to 5-h incubation in broth and use of different agar media. Results obtained using these modifications were compared to the results obtained by the standard method. It was shown that the two modifications investigated had a significant effect on the interpretation of zone diameters. It was further shown that the standard Bauer-Kirby method with some exceptions correlates with minimal inhibitory concentrations as determined by broth dilution methods. Results suggest that the Bauer-Kirby method may be a reliable technique for testing the antibiotic susceptibility of the nonfermentative bacilli.

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“…During a two-week period, all inpatient bacteriologic culture reports (1,381) were monitored, and ongoing chart review was conducted for all newly admitted patients (436) who had cultures taken; 17% of the infections had no cultures taken when indicated. The average bacteriology laboratory cost to each of these 436 patients was-$37.…”

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confidence: 99%

Ordering patterns and utilization of bacteriologic culture reports

Edwards¹

1973

Archives of Internal Medicine

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Selection of Antimicrobial Agents by Laboratory Means

Cited by 19 publications

References 12 publications

Antibiotic Activity in the Presence of Agar

Antibiotic Activity in the Presence of Agar

Antibiotic Susceptibility Testing of Gram-Negative Nonfermentative Bacilli

Ordering patterns and utilization of bacteriologic culture reports

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