Selection of complementary foods based on optimal nutritional values

Sen, Partho; Mardinogulu, Adil; Nielsen, Jens

doi:10.1038/s41598-017-05650-0

Cited by 14 publications

(12 citation statements)

References 51 publications

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“…Meta-analysis of transcriptomics datasets and genome-scale metabolic modelling In order to understand the regulation of metabolic pathways in PBMCs after seroconversion and type 1 diabetes progression, genome-scale metabolic models (GEMs) [12,[32][33][34] of PBMCs were developed. Gene expression or transcriptomics datasets were used to contextualise these models for the P1Ab, P1TD and CTRL groups.…”

Section: Methodsmentioning

confidence: 99%

“…ebi.ac.uk; accession number E-MTAB-1724). Expression data for 15 non-progressors (P1Ab), 51 cases of type 1 diabetes (PT1D), and their controls (CTRL) were selected for genomescale metabolic modelling (GSMM) [12,[32][33][34]. In addition, differential expression of genes (DEG) for P1Ab vs CTRL, PT1D vs CTRL and PT1D vs P1Ab groups was performed.…”

Section: Methodsmentioning

confidence: 99%

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Metabolic alterations in immune cells associate with progression to type 1 diabetes

et al. 2020

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Aims/hypothesis Previous metabolomics studies suggest that type 1 diabetes is preceded by specific metabolic disturbances. The aim of this study was to investigate whether distinct metabolic patterns occur in peripheral blood mononuclear cells (PBMCs) of children who later develop pancreatic beta cell autoimmunity or overt type 1 diabetes. Methods In a longitudinal cohort setting, PBMC metabolomic analysis was applied in children who (1) progressed to type 1 diabetes (PT1D, n = 34), (2) seroconverted to ≥1 islet autoantibody without progressing to type 1 diabetes (P1Ab, n = 27) or (3) remained autoantibody negative during follow-up (CTRL, n = 10). Results During the first year of life, levels of most lipids and polar metabolites were lower in the PT1D and P1Ab groups compared with the CTRL group. Pathway over-representation analysis suggested alanine, aspartate, glutamate, glycerophospholipid and sphingolipid metabolism were over-represented in PT1D. Genome-scale metabolic models of PBMCs during type 1 diabetes progression were developed by using publicly available transcriptomics data and constrained with metabolomics data from our study. Metabolic modelling confirmed altered ceramide pathways, known to play an important role in immune regulation, as specifically associated with type 1 diabetes progression.Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00125-020-05107-6) contains peer-reviewed but unedited supplementary material, which is available to authorised users.* Partho Sen partho.sen@utu.fi * Mikael Knip

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Metabolic alterations in immune cells associate with progression to type 1 diabetes

et al. 2020

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“…Improper food selection at this stage is associated with a high prevalence of malnutrition in children under 5 years, [23]. The adequate complementary feeding of the breastfed child is critical for the optimal child growth and development.…”

Section: Selection Of Complementary Foodsmentioning

confidence: 99%

“…Fortified Complementary Foods are specifically formulated with appropriate nutritional quality to provide additional energy and nutrients to complement the family foods derived from the local diet by providing those nutrients which are either lacking or are present in insufficient quantities typically, cereal-based porridges with added vitamins and minerals [23].…”

Section: Fortified Complementary Foodsmentioning

confidence: 99%

Review on Quality Characteristics of Complementary Food and Look for Policy Gap in Case of Ethiopia

Seboka¹

2019

AJHR

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Malnutrition is the main factor for mortality and morbidity of children in developing countries. In Ethiopia 57% of death of children under 5 year of age are due to malnutrition. Inappropriate complementary feeding practices and it underlies more than one-third of child mortality in Ethiopia. Baby's growth and development is dependent on the type and amount of nourishment gets. Breast milk and the quality of complementary food play important role in baby's growth. When breast milk is no longer enough to meet the nutritional needs of the infant, complementary foods should be added to the diet of the child. The transition from exclusive breastfeeding to family foods, referred to as complementary feeding, during the period of complementary feeding, children are at high risk of under nutrition. Complementary foods are often of inadequate nutritional quality, or they are given too early or too late, in too small amounts, or not frequently enough. So consuming quality complementary foods should be given. The Guiding principles for complementary feeding of the breast feed child, set standards for developing locally appropriate feeding recommendations. They provide guidance on desired feeding behaviors as well as on the amount, consistency, energy density and nutrient content of foods. For energy, 200, 300, and 550 kcal per day is expected to be covered by complementary foods at 6-8, 9-11, and 12-23 months, respectively In addition, the complementary foods must provide relatively large proportions of micronutrients such as iron, zinc, phosphorus, magnesium, calcium, and vitamin-A. Complementary feeding should be timely, meaning that all infants should start receiving foods in addition to breast milk from 6 months onwards. It should be adequate, meaning that the complementary foods should be given in amounts and consistency and using a variety of foods to cover the nutritional needs of the growing child while maintaining breastfeeding.

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“…Pemilihan makan yang tepat berhubungan dengan prevalensi malnutrisi pada anak Balita. Hasil penelitian di 4 Benua menemukan bahwa ham babi yang diawetkan, pudding ikan, putih telur, buah quark, keju quarg, dan kri keju memiliki kandungan laktosa yang sama pada ASI (Sen, Mardinogulu, & Nielsen, 2017…”

Section: Hasil Dan Pembahasan Identifikasi Kondisi Dan Tingkat Pemahaunclassified

Penyusunan Media Informasi Tentang Praktik Pemberian Makan Untuk Mencegah Stunting Pada Anak Baduta

Setyowati¹,

Sofiyanti²,

Windayanti³

2018

ijm

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Pemberian gizi yang benar pada 1000 hari pertama kehidupan akan menentukan kualitas hidup seorang manusia. Dampak yang ditimbulkan malnutrisi pada periode ini akan bersifat permanen dan berjangka panjang. Praktik pemberiangizi yang tidak benar merupakan penyebab utama awal terjadinya stunting.Insiden malnutrisi meningkat tajam karena ketidaktahuan dan ketidakmampuan menyiapkan makanan bergizi bagi anaknya. Ketidaktahuan ini salah satu penyebabnya karena belum adanya media informasi pendukung terkait praktik pemberian makan pada Baduta yang sesuai dengan kondisi daerah setempat.Penelitian ini secara umum bertujuan untuk menganalisis tingkat pemahaman ibu tentang pemberian nutrisi pada baduta dan menyusun media media informasi yang efektifkepada ibu yang mempunyai baduta tentang praktik pemberian nutrisi, sehingga dapat secara efektif meningkatkan pemahaman ibu tentang praktik pemberian makan yang dapat mencukupi kebutuhan gizi seimbang, dan higienis.Sejalan dengan tujuan yang ingin dicapai dalam penelitian ini, maka penelitian ini menggunakan metode action research. Metode ini dipilih karena pada tahap pertama dilakukan kajian (research) terhadap kondisi dan tingkat pemahaman ibu yang mempunyai Baduta tentang praktik pemberian makan serta penyusunan suatu media informasi tentang praktik pemberian nutrisi yang efektif. Kemudian pada tahap kedua akan dilaksanakan implementasi/tindakan (action) untuk menerapkan serta menguji penerapan dan keefektifan pemanfaatan media informasi yang diberikan di lingkungan Bidan Praktik Mandiri, Rumah Bersalin dan Puskesmas.

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Selection of complementary foods based on optimal nutritional values

Cited by 14 publications

References 51 publications

Metabolic alterations in immune cells associate with progression to type 1 diabetes

Metabolic alterations in immune cells associate with progression to type 1 diabetes

Review on Quality Characteristics of Complementary Food and Look for Policy Gap in Case of Ethiopia

Penyusunan Media Informasi Tentang Praktik Pemberian Makan Untuk Mencegah Stunting Pada Anak Baduta

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