Selective fungitoxicity of cyclohexylamine and related aromatic amines

Gindrat, D.

doi:10.1007/bf01989896

Cited by 1 publication

(1 citation statement)

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“…Cyclohexylamine, protoporphyrin IX, solasodine, astragalin, and tryptophol, which play important roles in resisting oxidation reactions, as well as anti‐pathogen and anti‐inflammation functions, were isolated from downregulated DRMs in positive ion mode (Table 1 ). Cyclohexylamine is toxic to the fungus Pythium ultimum (Gindrat, 1981 ), but its anti‐viral effect has not been reported. In vitro, protoporphyrin IX and derivatives show broad antiviral activities (Cruz‐Oliveira et al, 2017 ; Figueira et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

Xanthohumol and echinocystic acid induces PSTVd tolerance in tomato

Tang,

Liu

et al. 2024

Plant Direct

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Tomato is a popular vegetable worldwide; its production is highly threatened by infection with the potato spindle tuber viroid (PSTVd). We obtained the full‐length genome sequence of previously conserved PSTVd and inoculated it on four genotypes of semi‐cultivated tomatoes selected from a local tomato germplasm resource. SC‐5, which is a PSTVd‐resistant genotype, and SC‐96, which is a PSTVd‐sensitive genotype, were identified by detecting the fruit yield, plant growth, biomass accumulation, physiological indices, and PSTVd genome titer after PSTVd inoculation. A non‐target metabolomics study was conducted on PSTVd‐infected and control SC‐5 to identify potential anti‐PSTVd metabolites. The platform of liquid chromatography‐mass spectrometry detected 158 or 123 differential regulated metabolites in modes of positive ion or negative ion. Principal component analysis revealed a clear separation of the global metabolite profile between PSTVd‐infected leaves and control regardless of the detection mode. The potential anti‐PSTVd compounds, xanthohumol, oxalicine B, indole‐3‐carbinol, and rosmarinic acid were significantly upregulated in positive ion mode, whereas echinocystic acid, chlorogenic acid, and 5‐acetylsalicylic acid were upregulated in negative ion mode. Xanthohumol and echinocystic acid were detected as the most upregulated metabolites and were exogenously applied on PSTVd‐diseased SC‐96 seedlings. Both xanthohumol and echinocystic acid had instant and long‐term inhibition effect on PSTVd titer. The highest reduction of disease symptom was induced by 2.6 mg/L of xanthohumol and 2.0 mg/L of echinocystic acid after 10 days of leaf spraying, respectively. A superior effect was seen on echinocystic acid than on xanthohumol. Our study provides a statistical basis for breeding anti‐viroid tomato genotypes and creating plant‐originating chemical preparations to prevent viroid disease.

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Section: Discussionmentioning

confidence: 99%