“…The first class is found in massive materials or submicronic particles: the susceptibility is large, the magnetization increases massively with the magnetic field intensity, a remnant magnetization occurs after removal of the magnetic field and, above a critical temperature called the Curie temperature (Tc), the ferroor ferri-magnetic behavior disappears. The largest [18,20,[85][86][87][88][89][90][91] Micelles Based on surfactants or block copolymers <50 Drug carriers potentially thermo-, photo-or pH-sensitive [18,20,[85][86][87][88][89][90][91] Biodegradable polymeric capsules or spheres Polylactide, poly(lactic-coglycolic acid) and polyalkylcyanoacrylate 10-1000 Drug carriers potentially thermo-, photo-or pH-sensitive [18,20,[85][86][87][88][89][90][91] Inorganic Semiconductor quantum dots CdS 2-8 Fluorescent probes for optical diagnosis [2] Noble metal colloids Gold and silver 2-20 Fluorescent probes for optical diagnosis; light-guided and light-activated therapies [3] Magnetic [6][7][8][9][10][11][12][13] Magnetic nanoparticles and their applications in medicine -REVIEW iron oxide nanoparticles belong to this class (e.g., Tc = 580°C for Fe 3 O 4 ). If their size is lower than approx 10-20 nm, iron oxide nanoparticles are said to be 'superparamagnetic' and their main feature is the absence of remnant magnetization, limiting magnetic interactions within particles and, therefore, facilitating their stabi...…”