Selective laser sintered bio-inspired silicon-wollastonite scaffolds for bone tissue engineering

Kamboj, Nikhil; Kazantseva, Jekaterina; Rahmani, Ramin; Rodrı́guez, Miguel Á.; Hussainova, Irina

doi:10.1016/j.msec.2020.111223

Cited by 50 publications

(35 citation statements)

References 49 publications

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“…If energy is spent on (1) plastic, (2) elastic deformation, or (3) fracture of material, then the acceleration will be lower. The implemented test method can be used for a wide range of material types, such as ceramics or bioceramics, metal alloys, hard materials, and hybrid composites produced by SPS and/or SLM or other methods as additional characterization criteria [28][29][30][31]. The size of the indent can be used as an indication of "dynamic hardness."…”

Section: Resultsmentioning

confidence: 99%

The Impact Resistance of Highly Densified Metal Alloys Manufactured from Gas-Atomized Pre-Alloyed Powders

2021

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With the increasing acceleration of three-dimensional (3D) printing (for example, powder bed fusion (PBF)) of metal alloys as an additive manufacturing process, a comprehensive characterization of 3D-printed materials and structures is inevitable. The purpose of this work was to test highly densified materials produced from gas-atomized pre-alloyed metallic powders, namely 316L, Ti6Al4V, AlSi10Mg, CuNi2SiCr, CoCr28Mo6, and Inconel718, under impact conditions. This was done to demonstrate the best possible performance of such materials. Optimized spark plasma sintering (SPS) parameters (pressure, temperature, heating rate, and holding time) are applied as a novel technique of powder metallurgy. The densification level, impact site (imprint) diameter and volume, and Vickers hardness were studied. The comparison of 316L stainless steel (1) sintered by the SPS process, (2) manufactured by PBF process, and (3) coated by the physical vapor deposition (PVD) process (thin layer of TiAlN) was successfully achieved.

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Section: Resultsmentioning

confidence: 99%

The Impact Resistance of Highly Densified Metal Alloys Manufactured from Gas-Atomized Pre-Alloyed Powders

2021

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“…Arrows between two cellularization pathways indicate that techniques initially developed for a given cellularization pathway evolved to allow for other cellularization pathway. Selected references are cited for each technique.fabrication techniquepore size (µm)cellularization typeselected referencestemperature-induced phase separation10–400I[230–232]ice templating0.5–1300I → II[37,40,41,233]solvent casting/particulate leaching20–600I[57,58,60]gas foaming>30I[70,71,234–236]electrospinning0.2–400I → II[91,93,98]selective laser sintering>50I[106,237–240]fused deposition modelling>150I[125,219,241,242]stereolithography>20I → II[142,243–245]bioprinting>20II[148,169,246]microencapsulation2–1500…”

Section: Discussionmentioning

confidence: 99%

Colonization versus encapsulation in cell-laden materials design: porosity and process biocompatibility determine cellularization pathways

Parisi

Qin

Fernandes

2021

Phil. Trans. R. Soc. A.

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Seeding materials with living cells has been—and still is—one of the most promising approaches to reproduce the complexity and the functionality of living matter. The strategies to associate living cells with materials are limited to cell encapsulation and colonization, however, the requirements for these two approaches have been seldom discussed systematically. Here we propose a simple two-dimensional map based on materials' pore size and the cytocompatibility of their fabrication process to draw, for the first time, a guide to building cellularized materials. We believe this approach may serve as a straightforward guideline to design new, more relevant materials, able to seize the complexity and the function of biological materials. This article is part of the theme issue ‘Bio-derived and bioinspired sustainable advanced materials for emerging technologies (part 1)’.

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“…This can be attributed to the lower absorbance of silicate-based bioceramics under the impact of the Nd:YAG laser [ 149 ]. The prospects of fabricating novel silicate-based bioceramics and silicate-based bioglass scaffolds (designed by the phase diagram of CaSiO 3 –Ca 3 (PO 4 ) 2 –MgCa(SiO 3 ) 2 ) by incorporating silicon in the powder bed through Nd:YAG laser are shown in [ 17 , 95 , 150 ]. The potential of pore-driven osteogenesis and sustained delivery of antibiotic vancomycin through silicon-based bioceramic scaffolds was also disclosed [ 35 , 150 ].…”

Section: Bioactive Ceramic Scaffolds Processed By Pbslpmentioning

confidence: 99%

“…The prospects of fabricating novel silicate-based bioceramics and silicate-based bioglass scaffolds (designed by the phase diagram of CaSiO 3 –Ca 3 (PO 4 ) 2 –MgCa(SiO 3 ) 2 ) by incorporating silicon in the powder bed through Nd:YAG laser are shown in [ 17 , 95 , 150 ]. The potential of pore-driven osteogenesis and sustained delivery of antibiotic vancomycin through silicon-based bioceramic scaffolds was also disclosed [ 35 , 150 ]. Silicon has already displayed its potential in biocalcification, biomineralization, osteogenesis, and BTE [ 151 , 152 , 153 ].…”

Section: Bioactive Ceramic Scaffolds Processed By Pbslpmentioning

confidence: 99%

“…The main advantage associated with the synthetic bioactive ceramic bone grafts fabricated through SLM/SLS is the ability to fine-tune the mechanical properties and administer degradation rate. Additionally, the bioactive ceramic-based scaffolds fabricated by SLM possess the potential to be used for both cortical and trabecular bone applications [ 17 , 150 ].…”

Section: Synthetic Bioactive Ceramic Scaffolds For Critical Size Bone Defects By Pbslpmentioning

confidence: 99%

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Bioactive Ceramic Scaffolds for Bone Tissue Engineering by Powder Bed Selective Laser Processing: A Review

2021

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The implementation of a powder bed selective laser processing (PBSLP) technique for bioactive ceramics, including selective laser sintering and melting (SLM/SLS), a laser powder bed fusion (L-PBF) approach is far more challenging when compared to its metallic and polymeric counterparts for the fabrication of biomedical materials. Direct PBSLP can offer binder-free fabrication of bioactive scaffolds without involving postprocessing techniques. This review explicitly focuses on the PBSLP technique for bioactive ceramics and encompasses a detailed overview of the PBSLP process and the general requirements and properties of the bioactive scaffolds for bone tissue growth. The bioactive ceramics enclosing calcium phosphate (CaP) and calcium silicates (CS) and their respective composite scaffolds processed through PBSLP are also extensively discussed. This review paper also categorizes the bone regeneration strategies of the bioactive scaffolds processed through PBSLP with the various modes of functionalization through the incorporation of drugs, stem cells, and growth factors to ameliorate critical-sized bone defects based on the fracture site length for personalized medicine.

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Selective laser sintered bio-inspired silicon-wollastonite scaffolds for bone tissue engineering

Cited by 50 publications

References 49 publications

The Impact Resistance of Highly Densified Metal Alloys Manufactured from Gas-Atomized Pre-Alloyed Powders

The Impact Resistance of Highly Densified Metal Alloys Manufactured from Gas-Atomized Pre-Alloyed Powders

Colonization versus encapsulation in cell-laden materials design: porosity and process biocompatibility determine cellularization pathways

Bioactive Ceramic Scaffolds for Bone Tissue Engineering by Powder Bed Selective Laser Processing: A Review

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