Selective Monitoring of Organophosphorus Pesticides by 31P-NMR Spectroscopy: Application to Purity Assay of Technical Products and Concentration Determination of Formulated Samples

Ultrasensitive Detection of Organophosphorus Pesticides Using Single-Molecule Conductance Measurement

“…Organophosphorus pesticides (OPs) have been used extensively to eradicate insects in agricultural areas across the world in recent decades. , And OPs are an ensemble of strictly regulated toxic compounds that have harmful effects on humans and animals when the residues are in low amounts of 55.2 pM (10 –12 mol/L). , The toxic effects of OPs make them inhibit the activity of acetylcholinesterase, which causes interruption of neurotransmitter transmission and eventually death. − Although colorimetric systems were widely employed to detect OPs, the severe interference of sensitivity and selectivity about OPs caused by color limited their applications in practical samples. − To overcome the interference by color, lots of efforts had been made in the past years, such as microarray, , capillary electrophoresis, liquid chromatography, nuclear magnetic resonance, and mass spectrometry . However, most of these methods required time-consuming sample pretreatment, the use of other materials for signal amplification, low sensitivity, and sophisticated instrument manipulation.…”

“…5−7 Although colorimetric systems were widely employed to detect OPs, the severe interference of sensitivity and selectivity about OPs caused by color limited their applications in practical samples. 8−10 To overcome the interference by color, lots of efforts had been made in the past years, such as microarray, 11,12 capillary electrophoresis, 13 liquid chromatography, 14 nuclear magnetic resonance, 15 and mass spectrometry. 16 However, most of these methods required timeconsuming sample pretreatment, the use of other materials for signal amplification, low sensitivity, and sophisticated instrument manipulation.…”

A computational approach to design an electrochemical sensor and determination of acephate in aqueous solution based on a molecularly imprinted poly(o-phenylenediamine) film

“…To date, several analytical methods have been used for the determination of OPPs based on gas chromatography (GC) and high performance liquid chromatography (HPLC) such as GCmass spectrometry, 8 GC-solid-phase microextraction, 9 GC-ame ionization detection, 10 HPLC-ultraviolet detection, 11 and UPLCmass spectrometry. 12 In addition, 31 P nuclear magnetic resonance spectroscopy, 13 chemiluminescent enzyme immunoassay, 14 and reversed electrode polarity stacking mode-micellar electrokinetic chromatography 15 have also been developed for detecting OPPs in recent years. Although most of these methods are eminently adequate in terms of their sensitivity and accuracy, the major disadvantages of the above methods are the use of expensive apparatuses, need for highly trained personnel, complexity, high consumption of organic solvents and requirement of several sample preparation procedures including extraction and preconcentration.…”