Selective Nitroxylation of Adamantane Derivatives in the System Nitric Acid–Acetic Anhydride

Synthesis of 2-Oxaadamantane Derivatives

“…We previously showed that the reaction of 1,3-di­chloroadamantane with fuming nitric acid, including in the presence of acetic anhydride, involves nitrolysis with the formation of 3-chloroadamantan-1-yl nitrate and adamantane-1,3-diyl dinitrate [ 44 , 45 ]. Change of the reaction conditions (no acetic anhydride, room temperature) led to the formation of a mixture of prod­ucts having 2-oxaadamantane structure.…”

“…The reaction proceeded through intermediate forma­tion of 3-chloro-5,7-dimethyladamantan-1-yl nitrate ( 5 ) and 5,7-dimethyladamantane-1,3-diyl dinitrate ( 6 ) [ 44 ]. After 10 min from the reaction start, the fractions of 2-oxaadamantanes 2 , 3 , and 4 were 9.3, 4.8, and 0.6%, respectively (GLC), and the fraction of nitroxy derivatives amounted to 85.3%.…”

Research and Design of Etching Line about Nuclear Track Membrane

“…This kind of membrane can serve the fields of medicine, food and beverage, chemical industry, electronics, energy, and environmental protection more efficiently. At present, domestic applications are widely used in medical equipment precision filtration, cancer cell detection, traditional Chinese medicine filtration, beer filtration, safety identification, anti-counterfeiting, sewage treatment, water filtration, air filtration and other fields, and the output and demand are increasing year by year [3][4][5]. After the nuclear track membrane is irradiated, the membrane is only a semi-finished and it needs to be etched to become a finished production, this process is indispensable.…”