2011
DOI: 10.1039/c0an00906g
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Selective solid phase extraction of propranolol on multiwell membrane filter plates modified with molecularly imprinted polymer

Abstract: Molecularly imprinted polymers (MIPs) were synthesized in 24-well glass fiber membrane filter plates to obtain a novel type of solid phase extraction device for the cleanup of propranolol. Sample processing parameters like residence time during sample loading, sample volume, pH, sample solvent, type and amount of washing and elution solvents were investigated and optimized. Important differences from the traditional molecularly imprinted solid phase extraction (MISPE) cartridges have been identified. The MIP m… Show more

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Cited by 27 publications
(16 citation statements)
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References 40 publications
(47 reference statements)
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“…The majority of reported molecularly imprinted membrane studies has as an ultimate goal, either process development (in particular for separation and purification) or incorporation with sensors . While efforts to develop and apply molecularly imprinted membranes continue, it remains clear that more work is required to address the mechanisms underlying membrane function.…”
Section: Applicationsmentioning
confidence: 99%
“…The majority of reported molecularly imprinted membrane studies has as an ultimate goal, either process development (in particular for separation and purification) or incorporation with sensors . While efforts to develop and apply molecularly imprinted membranes continue, it remains clear that more work is required to address the mechanisms underlying membrane function.…”
Section: Applicationsmentioning
confidence: 99%
“…Filter plates were modified by photo-copolymerization with methacrylic acid as functional monomer and EDMA as cross-linker [290]. …”
Section: Mims-based Bio-mimetic Sensorsmentioning
confidence: 99%
“…MIMs were also used to concentrate and analyze propanolol, a beta-blocker drug, in urine and blood samples, and work concerning this application was reported by Renkecz et al [60]. Oxprenolol was used as an analog to test membrane selectivity.…”
Section: Advanced Polymeric Membranes: Synthesis and Applicationsmentioning
confidence: 99%