Selenium health benefit values provide a reliable index of seafood benefits vs. risks

Ralston, Nicholas V.C.; Kaneko, J. John; Raymond, Laura J.

doi:10.1016/j.jtemb.2019.05.009

Cited by 67 publications

(34 citation statements)

References 68 publications

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“…Se and Hg tend to bind in fish tissue. When Se is present in excess of Hg in fish, there is no public health concern about Hg exposure from eating fish[ 95 , 96 ].…”

Section: Healthy Diet Includes Whole Foods and May Include Supplements When Warrantedmentioning

confidence: 99%

Connecting inorganic mercury and lead measurements in blood to dietary sources of exposure that may impact child development

Dufault¹,

Wolle²,

Kingston³

et al. 2021

WJM

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Pre-natal and post-natal chemical exposures and co-exposures from a variety of sources including contaminated air, water, soil, and food are common and associated with poorer birth and child health outcomes. Poor diet is a contributing factor in the development of child behavioral disorders. Child behavior and learning can be adversely impacted when gene expression is altered by dietary transcription factors such as zinc insufficiency or deficiency or by exposure to toxic substances permitted in our food supply such as mercury, lead, or organophosphate pesticide residue. Children with autism spectrum disorder and attention deficit hyperactivity disorders exhibit decreased or impaired PON1 gene activity which is needed by the body to metabolize and excrete neurotoxic organophosphate pesticides. In this current review we present an updated macroepigenetic model that explains how dietary inorganic mercury and lead exposures from unhealthy diet may lead to elevated blood mercury and/or lead levels and the development of symptoms associated with the autism and attention deficit-hyperactivity disorders. PON1 gene activity may be suppressed by inadequate dietary calcium, selenium, and fatty acid intake or exposures to lead or mercury. The model may assist clinicians in diagnosing and treating the symptoms associated with these childhood neurodevelopmental disorders. Recommendations for future research are provided based on the updated model and review of recently published literature.

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“…Se and Hg tend to bind in fish tissue. When Se is present in excess of Hg in fish, there is no public health concern about Hg exposure from eating fish[ 95 , 96 ].…”

Section: Healthy Diet Includes Whole Foods and May Include Supplements When Warrantedmentioning

confidence: 99%

Connecting inorganic mercury and lead measurements in blood to dietary sources of exposure that may impact child development

Dufault¹,

Wolle²,

Kingston³

et al. 2021

WJM

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show abstract

“…(Scherr et al, 2014) Sugere-se realizar uma correlação entre a concentração de mercúrio e a concentração de ácidos graxos poliinsaturados, para uma avaliação do risco e benefício do consumo dos peixes comumente consumidos em Minas Gerais. Outro nutriente que tem sido considerado nessas avaliações de risco e benefício é o selênio (Se), que tem se mostrado como um fator protetor a intoxicação por metilmercúrio em uma proporção molar Se/Hg superior a 1:1 (Bjørklund et al, 2017, Spiller, 2017, Ralston and Raymond, 2019.…”

Section: Mercúrio Total Nas Amostras De Peixesunclassified

Mercúrio em peixes comercializados em Minas Gerais e possíveis riscos associados ao seu consumo

Costa

Custódio

Silva

et al. 2020

RSD

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O objetivo do trabalho foi analisar o teor de mercúrio em peixes comercializados em Minas Gerais, coletados pelo Programa de Monitoramento de Alimentos da Vigilância Sanitária de Minas Gerais - PROGVISA, e verificar com base nesses valores o risco do consumo de peixes. Foi analisado o teor de mercúrio total em 80 amostras de peixes coletadas de forma aleatória no mercado de Minas Gerais. As análises foram feitas por espectrofotometria de absorção atômica após amalgamação em ouro. A partir desses valores foi estimada a ingestão de metilmercúrio em Minas Gerais e esta estimativa foi comparada com parâmetros toxicológicos de referência. Dentre as amostras, 38,8% eram de peixes não predadores e 61,2% eram de peixes predadores. Os resultados indicaram que os teores de mercúrio encontrados na maioria das amostras de peixes de Minas Gerais foram inferiores aos limites máximos permitidos pela legislação brasileira. Somente 8,2% das amostras de peixes predadores apresentaram resultados insatisfatórios (teores >1,0 mg/kg), sendo somente o peixe cação. Em geral, peixes não predadores e peixes usualmente de aquicultura, como tilápia, panga e salmão, apresentaram teores de mercúrio baixos. A ingestão de mercúrio estimada para a população de Minas Gerais foi considerada aceitável, sem risco apreciável à saúde. O consumo de peixes seguindo a recomendação de duas a três porções semanais, desde que não se inclua peixes do topo da cadeia alimentar, parece ser seguro. Os resultados indicam que teores de mercúrio abaixo dos limites estabelecidos pela legislação brasileira são importantes para garantir ingestões desse contaminante em níveis seguros.

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“…In the environment, Hg is a highly toxic metal without any known biological function; in fact, it is the element responsible of various environmental and human health problems, even at low concentrations Selenium is an essential metalloid that plays an important role in the formation of selenocysteine-rich proteins within the cells of most organisms (Stroud et al 2010;Vega-Sánchez et al 2020); it also intervenes in brain functions, growth, thyroid hormone metabolism, calcium regulation, and prevents/reverses oxidative stress in humans (Davy and Castellano 2018;Xu et al 2018;Ralston et al 2019). Selenium de ciency in human nutrition can lead to infertility (mainly in men) and diseases such as Keshán (heart muscle or myocardial involvement) and Kashin-Beck (osteoarticular involvement) (Yang et al 2008;Shreenath et al 2019), while at elevated levels, it can cause selenosis, which is characterized by hair loss, misshapen nails, rashes, swelling of the skin, and severe pain in the extremities (Raymond and Ralston 2004;Ahmad et al 2021).…”

Section: Introductionmentioning

confidence: 99%

Mercury and selenium concentrations in the oysters Saccostrea palmula and Crassostrea corteziensis from four coastal lagoons of NW Mexico: health risk assessment

Sepúlveda

Sotelo-Gonzalez

Osuna-Martínez

et al. 2021

Preprint

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Mercury (Hg) and selenium (Se) concentrations in the soft tissue of the oysters Saccostrea palmula and Crassostrea corteziensis from four coastal lagoons (Altata, Macapule, Navachiste, El Colorado) of Northwest Mexico were determined. A total of 2520 specimens of S. palmula and 3780 of C. corteziensis (72.15 ± 4.95 and 73.57 ± 5.31 mm, respectively) were sampled seasonally from summer 2019 to spring 2020. The higher Hg concentration (wet weight) for S. palmula (0.13 ± 0.03–0.11 ± 0.02 µg g−1) and C. corteziensis (0.12 ± 0.02–0.11 ± 0.03 µg g−1) were obtained in summer−autumn 2019; Hg level was similar among the coastal lagoons and did not exceed the limit established by Mexican legislation and by the Food and Drug Agency. The higher Se concentration occurred in spring 2020 for both oyster species in El Colorado lagoon (4.55 ± 0.02 and 4.08 ± 0.05 µg g−1, respectively). The Se/Hg molar ratio of S. palmula and C. corteziensis ranged from 48.76–149.59 and 31.72–155.37, respectively; while the Se health benefit value was 19.23–42.28 and 17.82–35.30, respectively. The hazard quotient for Hg -estimated as methylmercury- and Se in both species of oyster was below 1. The high molar ratio obtained (Se/Hg > 1) indicates that the concentration of Se was sufficient to neutralize the possible toxicity of the Hg, therefore, the consumption of S. palmula and C. corteziensis from the four coastal lagoons studied does not represent a risk.

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Selenium health benefit values provide a reliable index of seafood benefits vs. risks

Cited by 67 publications

References 68 publications

Connecting inorganic mercury and lead measurements in blood to dietary sources of exposure that may impact child development

Connecting inorganic mercury and lead measurements in blood to dietary sources of exposure that may impact child development

Mercúrio em peixes comercializados em Minas Gerais e possíveis riscos associados ao seu consumo

Mercury and selenium concentrations in the oysters Saccostrea palmula and Crassostrea corteziensis from four coastal lagoons of NW Mexico: health risk assessment

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