Self-assembled mesoporous particles of Antheraea pernyi silk fibroin for encapsulation and sustained release of 5-fluorouracil

Shan, D. C.; Wei, Yunhang; Tan, Yuhao; Li, Y.; Li, Jingliang; Wu, Ting; Han, Lu; Wang, Ming; Ahmed, Shaharia; Zhou, Weitao; Wu, Lingfeng; Zhang, Tianhui

doi:10.1016/j.colsurfa.2023.131772

Cited by 3 publications

(1 citation statement)

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“…With the treatment of acidic reagents (e.g., formic acid and trifluoroacetic acid) or ethanol, the secondary structure of RSF films is altered to modulate their biodegradability and mechanical properties for cell scaffold materials [128]. In fact, LiSCN is more commonly employed to dissolve Antheraea pernyi silk fibroin [129][130][131]. The RSF of Antheraea pernyi obtained by alkaline degumming and LiSCN solubilization showed considerable degradation, with dispersed molecular weight bands from 20 kDa to 150 kDa [130].…”

Section: Methods and Properties Of Rsf By Alkali Dissolutionmentioning

confidence: 99%

Advances in Preparation and Properties of Regenerated Silk Fibroin

Huang,

Shi,

Zhou

et al. 2023

IJMS

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Over the years, silk fibroin (SF) has gained significant attention in various fields, such as biomedicine, tissue engineering, food processing, photochemistry, and biosensing, owing to its remarkable biocompatibility, machinability, and chemical modifiability. The process of obtaining regenerated silk fibroin (RSF) involves degumming, dissolving, dialysis, and centrifugation. RSF can be further fabricated into films, sponges, microspheres, gels, nanofibers, and other forms. It is now understood that the dissolution method selected greatly impacts the molecular weight distribution and structure of RSF, consequently influencing its subsequent processing and application. This study comprehensively explores and summarizes different dissolution methods of SF while examining their effects on the structure and performance of RSF. The findings presented herein aim to provide valuable insights and references for researchers and practitioners interested in utilizing RSF in diverse fields.

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