Self-assembly of polypyrrole/chitosan composite hydrogels

Huang, Hao; Wu, Jiao; Lin, Xi; Liang, Li; Shang, Songmin; Yuen, Marcus Chun Wah; Yan, Guoping

doi:10.1016/j.carbpol.2013.02.071

Cited by 70 publications

(25 citation statements)

References 35 publications

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“…Molecular structure of cellulose/silk fibroin blend fiber FTIR has been comprehensively used to study the interaction of polymer blends (Shang et al 2009;Lü et al 2010Lü et al , 2011Huang et al 2013). The FTIR of cellulose/silk fibroin blend fiber is shown in Fig.…”

Section: Morphology Of Cellulose/silk Fibroin Blend Fibersmentioning

confidence: 99%

Morphology and properties of cellulose/silk fibroin blend fiber prepared with 1-butyl-3-methylimidazolium chloride as solvent

et al. 2014

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1-Butyl-3-methylimidazolium chloride ([BMIM]Cl) was selected as co-solvent to dissolve cellulose and silk fibroin and the cellulose/silk fibroin blend fibers were fabricated with dry-jet wet spinning technology. The phase morphology of cellulose and silk fibroin in the blend fibers was studied by scanning electron microcopy and laser scanning confocal microscope. It is shown that the cellulose is in the continuous phase and silk fibroin exists as ''fibril-like'' in cellulose, in which the radial dimension of silk fibroin phase is 0.5-1.0 lm. The phase size of silk fibroin along the fiber axis increased with the increase of silk fibroin content and draw ratio. From the wideangle X-ray scattering, it is found that the total crystallinity of the blend fibers decreased with increasing silk fibroin content. The hydrogen bond between cellulose and silk fibroin was observed from Fourier transform infrared spectra. Although the tensile strength and initial modulus of blend fibers decreased with increasing silk fibroin content, the tensile strength of blend fibers contain 35 wt% silk fibroin was up to 191 MPa.

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Section: Morphology Of Cellulose/silk Fibroin Blend Fibersmentioning

confidence: 99%

Morphology and properties of cellulose/silk fibroin blend fiber prepared with 1-butyl-3-methylimidazolium chloride as solvent

et al. 2014

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“…Since hydrogels can typically mimic the biomechanical and hydrated properties of native soft tissues, they are popular for use as biomimetic materials. In general, conductive hydrogels can be produced by incorporating (through polymerization or grafting) CPs into several synthetic and natural polymers . Some conductive hydrogels were produced for neural, cardiac, or myoblast culture studies.…”

Section: Introductionmentioning

confidence: 99%

Polypyrrole/Alginate Hybrid Hydrogels: Electrically Conductive and Soft Biomaterials for Human Mesenchymal Stem Cell Culture and Potential Neural Tissue Engineering Applications

et al. 2016

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Electrically conductive biomaterials that can efficiently deliver electrical signals to cells or improve electrical communication among cells have received considerable attention for potential tissue engineering applications. Conductive hydrogels are desirable particularly for neural applications, as they can provide electrical signals and soft microenvironments that can mimic native nerve tissues. In this study, conductive and soft polypyrrole/alginate (PPy/Alg) hydrogels are developed by chemically polymerizing PPy within ionically cross-linked alginate hydrogel networks. The synthesized hydrogels exhibit a Young's modulus of 20-200 kPa. Electrical conductance of the PPy/Alg hydrogels could be enhanced by more than one order of magnitude compared to that of pristine alginate hydrogels. In vitro studies with human bone marrow-derived mesenchymal stem cells (hMSCs) reveal that cell adhesion and growth are promoted on the PPy/Alg hydrogels. Additionally, the PPy/Alg hydrogels support and greatly enhance the expression of neural differentiation markers (i.e., Tuj1 and MAP2) of hMSCs compared to tissue culture plate controls. Subcutaneous implantation of the hydrogels for eight weeks induces mild inflammatory reactions. These soft and conductive hydrogels will serve as a useful platform to study the effects of electrical and mechanical signals on stem cells and/or neural cells and to develop multifunctional neural tissue engineering scaffolds.

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“…The design and fabrication of PCC with particular morphology and prediction structure of composite are still a big challenge. Herein, the strategy we develop within this study leads to a new kind of composite hydrogel [17].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and representation of a new structure for polypyrrole–chitosan nanocomposite and investigation of effect of intermolecular interaction

et al. 2014

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Self-assembly of polypyrrole/chitosan composite hydrogels

Cited by 70 publications

References 35 publications

Morphology and properties of cellulose/silk fibroin blend fiber prepared with 1-butyl-3-methylimidazolium chloride as solvent

Morphology and properties of cellulose/silk fibroin blend fiber prepared with 1-butyl-3-methylimidazolium chloride as solvent

Polypyrrole/Alginate Hybrid Hydrogels: Electrically Conductive and Soft Biomaterials for Human Mesenchymal Stem Cell Culture and Potential Neural Tissue Engineering Applications

Synthesis and representation of a new structure for polypyrrole–chitosan nanocomposite and investigation of effect of intermolecular interaction

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